Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 11/20 | 0.62 |
| ▸ | DRD2 | P14416 | 6/20 | 0.62 |
| ▸ | DRD5 | P21918 | 4/20 | 0.62 |
| ▸ | DRD1 | P21728 | 6/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6716162 | 0.84 | DRD3 (0.69) | DRD3DRD2DRD5DRD1HTR1A | |
| SCHEMBL6972081 | 0.80 | DRD3 (0.57) | DRD3DRD2DRD5DRD1HTR1A | |
| Hydrochloric Acid SCHEMBL6712934 | 0.79 | DRD3 (0.56) | DRD3DRD2DRD5DRD1HTR1A | |
| SCHEMBL6711645 | 0.77 | ALDH1A1 (0.48) | DRD3DRD2DRD5DRD1HTR1A | |
| SCHEMBL6711558 | 0.74 | DRD3 (0.56) | DRD3DRD2DRD5DRD1HTR1A | |
| SCHEMBL9725103 | 0.74 | ADRB1 (0.59) | DRD3DRD2DRD1HTR1AL3MBTL1 | |
| SCHEMBL6714657 | 0.74 | HRH4 (0.55) | DRD3DRD2DRD5HTR1AHTR7 | |
| SCHEMBL11631810 | 0.73 | DRD2 (0.72) | DRD3DRD2DRD5DRD1HTR1A | |
| SCHEMBL12968838 | 0.72 | ADRB1 (0.68) | L3MBTL1KDM4EADRB1ALDH1A1HSD17B10 | |
| SCHEMBL2799020 | 0.72 | ADRA1B (0.52) | DRD3DRD2DRD1HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138203-A1 | Bicyclic lactams and sulfonamides with 5-ht1a -affinity and use thereof for preventing and treating cerebral ischaemia | STEINER GERD | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138203-A1 | Bicyclic lactams and sulfonamides with 5-ht1a -affinity and use thereof for preventing and treating cerebral ischaemia | HTR1A, HTR5A, HTR2C | DRD3 178/4885DRD2 83/4885DRD5 120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.