Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439028 | 0.68 | ADRA1A (0.49) | HTR3ANISCHADRA1DADRA1A | |
| SCHEMBL7533765 | 0.67 | HTR3A (0.37) | HTR3A | |
| SCHEMBL31370737 | 0.66 | CHRM2 (0.46) | CHRM2CHRM1CHRM3HTR3A | |
| SCHEMBL3645858 | 0.66 | CHRM2 (0.46) | CHRM2CHRM1CHRM3HTR3A | |
| Hydrochloric Acid SCHEMBL3795018 | 0.65 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HTR3A | |
| SCHEMBL9444151 | 0.65 | HTR3A (0.38) | CHRM2CHRM1CHRM3HTR3A | |
| SCHEMBL24165642 | 0.61 | MEN1 (0.38) | MTORADKNISCH | |
| SCHEMBL7533769 | 0.61 | SLC6A2 (0.41) | — | |
| SCHEMBL1299321 | 0.60 | ADRA1A (0.52) | NISCHADRA1DADRA1A | |
| SCHEMBL9842899 | 0.60 | HTR1A (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058755-A2 | COMPOUND LIBRARIES OF IMIDAZO[1,5-A]PYRIDIN-3-YL DERIVATIVES AND RELATED HETEROBICYCLES FOR TARGETTING COMPOUNDS CAPABLE OF BINDING TO G-PROTEIN COUPLED RECEPTORS | BIOFOCUS PLC (GB) | 2004-07-15 | — | — | WO | disclosed |