SCHEMBL6763836

SCHEMBL6763836

CCOC(=O)NN1CCCCC1c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.45
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45
THRB P10828 1/20 0.45
HPGD P15428 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.43
BRD4 O60885 1/20 0.43
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
RIPK1 Q13546 2/20 0.42
ACHE P22303 1/20 0.42
HSD11B1 P28845 1/20 0.41
PRMT5 O14744 3/20 0.41
WDR77 Q9BQA1 3/20 0.41
CASP3 P42574 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
TRPC3 Q13507 1/20 0.41
TRPC6 Q9Y210 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8026883 0.83 HSD11B1 (0.48) KDM4EALDH1A1HPGDRIPK1HSD11B1
SCHEMBL3841906 0.79 RIPK1 (0.51) RIPK1HSD11B1
SCHEMBL8303313 0.79 TMEM97 (0.58) BRD4MAOAMAOBRIPK1HSD11B1
SCHEMBL26984487 0.79 TMEM97 (0.58) BRD4MAOAMAOBRIPK1HSD11B1
SCHEMBL27984087 0.76 KDM4E (0.50) KDM4EALDH1A1HPGDSMN1; SMN2BRD4
SCHEMBL8781820 0.75 CHRNB2 (0.49) RIPK1HSD11B1
SCHEMBL28783781 0.75 ATM (0.42) KDM4EALDH1A1THRBSMN1; SMN2MEN1
SCHEMBL6976464 0.74 RIPK1 (0.49) RIPK1HSD11B1
SCHEMBL8111442 0.73 CHRNB2 (0.53) RIPK1HSD11B1PRMT5WDR77
SCHEMBL8781621 0.72 CHRNB2 (0.46) RIPK1HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1165218-B1 DEVICE FOR MIXING AND REACTING MULTIPHASE GASEOUS AND LIQUID MIXTURES AND USE OF THIS DEVICE BAYER AG (DE) 2003-05-21 EP claimed
EP-4090695-A1 METHOD FOR THE PRODUCING A POLYCARBONATE WITH IMPROVED RECOVERY OF NON-REACTED DIARYLCARBONATE Covestro Deutschland AG (DE) 2022-11-23 EP disclosed
WO-2021144212-A1 METHOD FOR THE PRODUCING A POLYCARBONATE WITH IMPROVED RECOVERY OF NON-REACTED DIARYLCARBONATE COVESTRO DEUTSCHLAND AG (DE) 2021-07-22 WO disclosed
US-6726354-B1 Device for mixing and reacting multiphase gaseous and liquid mixtures and use of this device BAYER AKTIENGESELLSCHAFT (DE) 2004-04-27 US disclosed
US-6548691-B2 Reacting phosgene and monophenols in an inert solvent, in the presence of alkaline solution and nitrogen base catalyst maintaining a temperature below 50 degrees C BAYER AKTIENGESELLSCAFT (DE) 2003-04-15 US disclosed
US-20020077446-A1 Process for producing carbonic acid diaryl ester BAYER AKTIENGESELLSCHAFT (DE) 2002-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020077446-A1 Process for producing carbonic acid diaryl ester PHGDH, PGLS, PYGL GAA 784/4885KDM4E 2713/4885ALDH1A1 2954/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.