Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6770539 | 0.87 | SRC (0.39) | ALDH1A1HPGDDHODHSMN1; SMN2KMT2A | |
| SCHEMBL6770505 | 0.87 | OPRM1 (0.46) | MAPTNPSR1DHODHMGLLRAB9A | |
| SCHEMBL6766708 | 0.86 | RIPK2 (0.48) | RIPK2MAPTALDH1A1HPGDNPSR1 | |
| SCHEMBL6164978 | 0.86 | DHODH (0.41) | ALDH1A1DHODHMAPK13MAPK12MAPK11 | |
| SCHEMBL6777339 | 0.85 | CASP1 (0.39) | MAPTALDH1A1HPGDNPSR1DHODH | |
| SCHEMBL6772551 | 0.84 | DHODH (0.37) | RIPK2MAPTALDH1A1HPGDNPSR1 | |
| SCHEMBL6770575 | 0.84 | GPBAR1 (0.39) | MAPTDHODHMGLLRAB9ASMN1; SMN2 | |
| SCHEMBL6770636 | 0.84 | RIPK2 (0.35) | RIPK2MAPTDHODHMGLLCCR1 | |
| SCHEMBL6766574 | 0.82 | ALDH1A1 (0.39) | MAPTALDH1A1HPGDNPSR1DHODH | |
| SCHEMBL7490727 | 0.79 | L3MBTL1 (0.36) | MAPTALDH1A1DHODHMGLLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716856-B1 | CELL PROLIFERATIVE DISORDERS OR ALZHEIMER'S DISEASE; REDUCED TOXICITY; CDK/CYCLIN KINASE INHIBITORY ACTIVITY | PHARMACIA & TUBJOHN SPA (IT) | 2004-04-06 | — | — | US | disclosed |