Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL896013 | 1.00 | TSHR (0.52) | TSHRLMNATYRALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL943177 | 0.97 | TSHR (0.50) | TSHRLMNATYRALDH1A1HPGD | |
| SCHEMBL67740 | 0.97 | TSHR (0.55) | TSHRLMNATYRALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL2026535 | 0.94 | TSHR (0.52) | TSHRLMNATYRALDH1A1HPGD | |
| SCHEMBL424728 | 0.80 | TSHR (0.73) | TSHRLMNATYRALDH1A1HPGD | |
| SCHEMBL1127658 | 0.79 | SRD5A2 (0.68) | LMNAALDH1A1TDP1MAPTNPC1 | |
| SCHEMBL1538330 | 0.78 | TSHR (0.61) | TSHRLMNATYRALDH1A1HPGD | |
| Hydrogen Peroxide SCHEMBL28677809 | 0.74 | LMNA (0.71) | TSHRLMNATYRALDH1A1HPGD | |
| Methylamine SCHEMBL28294591 | 0.74 | TSHR (0.65) | TSHRLMNATYRALDH1A1HPGD | |
| SCHEMBL4371460 | 0.73 | TSHR (0.55) | TSHRLMNATYRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365471-B2 | Substituted phenylsulfur trifluoride and other like fluorinating agents | UBE INDUSTRIES, LTD. (JP) | 2016-06-14 | — | — | US | claimed |
| EP-2046735-B1 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDES AS FLUORINATING AGENTS | UBE INDUSTRIES (JP) | 2015-05-06 | — | — | EP | claimed |
| US-20140235898-A1 | Substituted Phenylsulfur Trifluoride and Other Like Fluorinating Agents | UBE INDUSTRIES, LTD. (JP) | 2014-08-21 | — | — | US | claimed |
| US-8710270-B2 | Substituted phenylsulfur trifluoride and other like fluorinating agents | UBE INDUSTRIES, LTD. (JP) | 2014-04-29 | — | — | US | claimed |
| US-8203003-B2 | 4-fluoropyrrolidine-2-carbonyl fluoride compounds and their preparative methods | UBE INDUSTRIES, LTD. (JP) | 2012-06-19 | — | — | US | claimed |
| US-20120083627-A1 | Method of Synthesis of Arylsulfur Trifluorides and Use as in situ Deoxofluorination Reagent | FLUOROTECH, LLC (US) | 2012-04-05 | — | — | US | claimed |
| US-20110275833-A1 | Novel 4-Fluoropyrrolidine-2-Carbonyl Fluoride Compounds and Their Preparative Methods | UBE INDUSTRIES, LTD. (JP) | 2011-11-10 | — | — | US | claimed |
| US-20110009672-A1 | Substituted Phenylsulfur Trifluoride and Other Like Fluorinating Agents | IM&T RESEARCH, INC. (US) | 2011-01-13 | — | — | US | claimed |
| WO-2010081014-A1 | NOVEL 4-FLUOROPYRROLIDINE-2-CARBONYL FLUORIDE COMPOUNDS AND THEIR PREPARATIVE METHODS | IM&T RESEARCH, INC. (US) | 2010-07-15 | — | — | WO | claimed |
| US-20100174096-A1 | Methods for Production of Optically Active Fluoropyrrolidine Derivatives | IM&T RESEARCH, INC. (US) | 2010-07-08 | — | — | US | claimed |
| EP-2046735-A2 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDE AND OTHER LIKE FLUORINATING AGENTS | IM&T Research, Inc. (US) | 2009-04-15 | — | — | EP | claimed |
| US-7381846-B2 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | IM&T RESEARCH, INC. (US) | 2008-06-03 | — | — | US | claimed |
| US-20080039660-A1 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | IM&T RESEARCH, INC. (US) | 2008-02-14 | — | — | US | claimed |
| WO-2008013550-A1 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDE AND OTHER LIKE FLUORINATING AGENTS | IM & T RESEARCH, INC. (US) | 2008-01-31 | — | — | WO | claimed |
| WO-2008014345-A2 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDE AND OTHER LIKE FLUORINATING AGENTS | IM & T RESEARCH, INC. (US) | 2008-01-31 | — | — | WO | claimed |
| US-7265247-B1 | E.g., 2,6-dimethyl-4-tert-butylphenylsulfur trifluoride and 4-chlorophenylsulfur trifluoride; especially for fluorinating target compounds that have one or more oxygen or oxygen-containing groups that are replaced by the introduction of one or more fluorine atoms. | IM&T RESEARCH, INC. (US) | 2007-09-04 | — | — | US | claimed |
| US-9365471-B2 | Substituted phenylsulfur trifluoride and other like fluorinating agents | UBE INDUSTRIES, LTD. (JP) | 2016-06-14 | — | — | US | disclosed |
| EP-2046735-B1 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDES AS FLUORINATING AGENTS | UBE INDUSTRIES (JP) | 2015-05-06 | — | — | EP | disclosed |
| WO-2008013550-A1 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDE AND OTHER LIKE FLUORINATING AGENTS | IM & T RESEARCH, INC. (US) | 2008-01-31 | — | — | WO | disclosed |
| US-7265247-B1 | E.g., 2,6-dimethyl-4-tert-butylphenylsulfur trifluoride and 4-chlorophenylsulfur trifluoride; especially for fluorinating target compounds that have one or more oxygen or oxygen-containing groups that are replaced by the introduction of one or more fluorine atoms. | IM&T RESEARCH, INC. (US) | 2007-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140235898-A1 | Substituted Phenylsulfur Trifluoride and Other Like Fluorinating Agents | PFAS, FRS2, FBL | TSHR 952/4885LMNA 3809/4885TYR 619/4885 |
| US-20110009672-A1 | Substituted Phenylsulfur Trifluoride and Other Like Fluorinating Agents | PFAS, FRS2, FBL | TSHR 952/4885LMNA 3809/4885TYR 619/4885 |
| US-20110275833-A1 | Novel 4-Fluoropyrrolidine-2-Carbonyl Fluoride Compounds and Their Preparative Methods | PFAS, AFF4, PAICS | TSHR 2379/4885LMNA 2794/4885TYR 2931/4885 |
| US-20100174096-A1 | Methods for Production of Optically Active Fluoropyrrolidine Derivatives | QDPR, FDPS, DPYD | TSHR 2800/4885LMNA 4164/4885TYR 595/4885 |
| US-20120083627-A1 | Method of Synthesis of Arylsulfur Trifluorides and Use as in situ Deoxofluorination Reagent | AFF2, BRD2, AFF4 | TSHR 2203/4885LMNA 2690/4885TYR 397/4885 |
| US-20080039660-A1 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | TST, DDT, ESD | TSHR 330/4885LMNA 4265/4885TYR 514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.