Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538033 | 0.90 | KIF11 (0.47) | CES2MAPTNPSR1GAALMNA | |
| SCHEMBL2055460 | 0.87 | ACLY (0.44) | CES2MAPTNPSR1GAALMNA | |
| SCHEMBL732747 | 0.87 | CES2 (0.38) | CES2MAPTNPSR1GAALMNA | |
| SCHEMBL12268183 | 0.86 | RAPGEF4 (0.37) | CES2MAPTNPSR1GAALMNA | |
| SCHEMBL700367 | 0.86 | NOTUM (0.45) | CES2MAPTNPSR1GAALMNA | |
| SCHEMBL5363665 | 0.82 | CES2 (0.47) | CES2MAPTNPSR1GAALMNA | |
| SCHEMBL28851206 | 0.82 | MAPT (0.36) | CES2MAPTNPSR1GAALMNA | |
| SCHEMBL5565766 | 0.82 | KIF11 (0.48) | MAPTLMNACA1CA2MMP1 | |
| SCHEMBL18331419 | 0.81 | TRPV4 (0.47) | CES2KIF11CNR1 | |
| SCHEMBL29705559 | 0.81 | TRPV4 (0.47) | CES2KIF11CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 469 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120040313-A | Preparation method of posaconazole starting material SM3 | 山东金城柯瑞化学有限公司 | 2025-05-27 | — | — | CN | claimed |
| CN-116814325-B | Cutting fluid for aluminum alloy and preparation method thereof | 山东创新金属科技有限公司 | 2025-02-28 | — | — | CN | claimed |
| CN-116814325-A | Cutting fluid for aluminum alloy and preparation method thereof | 山东创新金属科技有限公司 | 2023-09-29 | — | — | CN | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| CN-121202849-B | Coumarin-pyrazole ring hybridization derivative and preparation method and application thereof | NORTHWEST UNIVERSITY (CN) | 2026-05-26 | — | — | CN | disclosed |
| US-12630529-B2 | GCN2 modulator compounds | Alesta Therapeutics BV (NL) | 2026-05-19 | — | — | US | disclosed |
| CN-120040313-B | Preparation method of posaconazole starting material SM3 | 山东金城柯瑞化学有限公司 | 2025-07-15 | — | — | CN | disclosed |
| CN-120040313-A | Preparation method of posaconazole starting material SM3 | 山东金城柯瑞化学有限公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-120040313-A | Preparation method of posaconazole starting material SM3 | 山东金城柯瑞化学有限公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-119101040-B | Method for synthesizing aryl substituted chiral tetrahydropyran ring through desymmetrical synthesis | 杭州澳赛诺医药技术有限公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-116814325-B | Cutting fluid for aluminum alloy and preparation method thereof | 山东创新金属科技有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119264303-A | Pendant group functionalized fluorine-containing polymer, preparation method of fluorine-containing polymer, ion exchange membrane and application | 佛山绿动氢能科技有限公司 | 2025-01-07 | — | — | CN | disclosed |
| EP-0628316-A1 | 19F-MRI contrast medium, having a macrocyclic complexant moiety | TERUMO KABUSHIKI KAISHA (JP) | 1994-12-14 | — | — | EP | disclosed |
| EP-0592306-A2 | 19F-MRI Contrast medium | TERUMO KABUSHIKI KAISHA (JP) | 1994-04-13 | — | — | EP | disclosed |
| US-4871843-A | TREATMENT OF NERVOUS SYSTEM DISORDERS WITH ANXIETY | DROPIC-SOCIETE CIVILE DE GESTION DE DROITS DE PROPRIETE INDUSTRIELLE (FR) | 1989-10-03 | — | — | US | disclosed |
| US-4760062-A | Anxiolytic agent | DROPIC, SOCIETE CIVILE DE GESTION DE DROITS DE PROPRIETE INDUSTRIELLE (FR) | 1988-07-26 | — | — | US | disclosed |
| US-4585769-A | PSYCHOTROPIC AGENTS | DROPIC - SOCIETE CIVILE DE GESTION DE DROITS DE PROPRIETE INDUSTRIELLE CHOAY (FR) | 1986-04-29 | — | — | US | disclosed |
| US-4507315-A | Hypoglycaemic and hypolipidaemic benzamide substituted (1H-) imidazole derivatives and compositions | MAY & BAKER LIMITED (GB) | 1985-03-26 | — | — | US | disclosed |
| US-4005199-A | Substituted benzenesulfonamides as anthelmintics | MERCK & CO., INC. (US) | 1977-01-25 | — | — | US | disclosed |
| US-3987199-A | PARASITICIDES | MERCK & CO., INC. (US) | 1976-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630529-B2 | GCN2 modulator compounds | NR3C1, GCN1, EIF2AK4 | CES2 2191/4885MAPT 4614/4885NPSR1 1323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.