Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.33 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18701550 | 0.85 | CA12 (0.44) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL5417010 | 0.85 | LMNA (0.36) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL12783372 | 0.83 | ALDH1A1 (0.43) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL13895343 | 0.83 | MMP1 (0.38) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL5421489 | 0.81 | MMP1 (0.37) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL20672069 | 0.81 | MLYCD (0.38) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL13849297 | 0.81 | MMP1 (0.37) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL20988354 | 0.81 | MMP1 (0.37) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL6840421 | 0.80 | LMNA (0.40) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL20053673 | 0.79 | CA12 (0.48) | LMNAMMP1MMP2MMP3MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446019-B1 | WATER CONTINUOUS FOOD PRODUCT WITH COOLING FLAVOUR | UNILEVER NV (NL) | 2007-03-14 | — | — | EP | claimed |
| CN-114929681-B | Bicyclic CX3CR1 receptor agonists | 德州大学系统董事会 | 2024-05-14 | — | — | CN | disclosed |
| US-11820728-B2 | Carbonyl lipids and lipid nanoparticle formulations for delivery of nucleic acids | Acuitas Therapeutics, Inc. (CA) | 2023-11-21 | — | — | US | disclosed |
| US-11820728-B2 | Carbonyl lipids and lipid nanoparticle formulations for delivery of nucleic acids | Acuitas Therapeutics, Inc. (CA) | 2023-11-21 | — | — | US | disclosed |
| US-20230322793-A1 | 10-(di(phenyl)methyl)-4-hydroxy-8,9,9A,10-tetrahydro-7H-pyrrolo[1 ',2':4,5]pyrazino[1,2-B]pyridazine-3,5-dione Derivatives and Related Compounds as Inhibitors of the Orthomyxovirus Replication for Treating Influenza | NOVARTIS AG (CH) | 2023-10-12 | — | — | US | disclosed |
| US-20230322793-A1 | 10-(di(phenyl)methyl)-4-hydroxy-8,9,9A,10-tetrahydro-7H-pyrrolo[1 ',2':4,5]pyrazino[1,2-B]pyridazine-3,5-dione Derivatives and Related Compounds as Inhibitors of the Orthomyxovirus Replication for Treating Influenza | NOVARTIS AG (CH) | 2023-10-12 | — | — | US | disclosed |
| US-20230227437-A1 | IMMUNOMODULATOR | HITGEN INC (CN) | 2023-07-20 | — | — | US | disclosed |
| US-20230227437-A1 | IMMUNOMODULATOR | HITGEN INC (CN) | 2023-07-20 | — | — | US | disclosed |
| US-20230159465-A1 | IMMUNOMODULATOR | HITGEN INC. (CN) | 2023-05-25 | — | — | US | disclosed |
| US-20230159465-A1 | IMMUNOMODULATOR | HITGEN INC. (CN) | 2023-05-25 | — | — | US | disclosed |
| US-20070043023-A1 | Modulators of muscarinic receptors | VERTEX PHARMACEUTICALS INCORPORATED | 2007-02-22 | — | — | US | disclosed |
| US-20070004675-A1 | Inhibitors of VEGF receptor and HGF receptor signaling | METHYLGENE, INC. | 2007-01-04 | — | — | US | disclosed |
| EP-0808849-B1 | Process for the production of ethylenic polymers | SHOWA DENKO KK (JP) | 2001-12-19 | — | — | EP | disclosed |
| US-6011127-A | CATALYST COMPRISING A CHROMIUM COMPOUND, AN ALUMOXANE AND AN ORGANOMETALLIC ALKOXIDE AND/OR ORGANOMETALLIC SILOXIDE AND A CARRIER SUPPORTING THEREON THESE COMPOUNDS. | SHOWA DENKO K.K. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0808849-A1 | Process for the production of ethylenic polymers | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1997-11-26 | — | — | EP | disclosed |
| US-4419282-A | N,N-Dimethyloctanamide fragrances | RHONE-POULENC INDUSTRIES (FR) | 1983-12-06 | — | — | US | disclosed |
| US-4419281-A | N,N-Diethylheptanamide fragrances | RHONE-POULENC INDUSTRIES (FR) | 1983-12-06 | — | — | US | disclosed |
| US-4301021-A | PERFUMES | RHONE-POULENC INDUSTRIES (FR) | 1981-11-17 | — | — | US | disclosed |
| US-4190643-A | P-METHANE-3-CARBOXAMIDES STIMULANTS | WILKINSON SWORD LIMITED (GB) | 1980-02-26 | — | — | US | disclosed |
| US-4141992-A | Cycloalkylcarboxyamidines and halobenzamidines as anti-amebic agents | AMERICAN CYANAMID COMPANY (US) | 1979-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159465-A1 | IMMUNOMODULATOR | IL2, IL17A, IL2RA | LMNA 4848/4885MMP1 1870/4885MMP2 1924/4885 |
| US-20070004675-A1 | Inhibitors of VEGF receptor and HGF receptor signaling | HGF, MET, FLT1 | LMNA 4411/4885MMP1 1074/4885MMP2 538/4885 |
| US-20230227437-A1 | IMMUNOMODULATOR | IL17A, IL2, IL2RA | LMNA 4866/4885MMP1 1781/4885MMP2 1830/4885 |
| US-11820728-B2 | Carbonyl lipids and lipid nanoparticle formulations for delivery of nucleic acids | TTPA, ACAA2, CPT2 | LMNA 12/4885MMP1 3912/4885MMP2 3243/4885 |
| US-20230322793-A1 | 10-(di(phenyl)methyl)-4-hydroxy-8,9,9A,10-tetrahydro-7H-pyrrolo[1 ',2':4,5]pyrazino[1,2-B]pyridazine-3,5-dione Derivatives and Related Compounds as Inhibitors of the Orthomyxovirus Replication for Treating Influenza | MAVS, ZC3HAV1, EIF2AK2 | LMNA 2139/4885MMP1 605/4885MMP2 702/4885 |
| US-20070043023-A1 | Modulators of muscarinic receptors | CHRM3, CHRM5, CHRM2 | LMNA 4093/4885MMP1 4332/4885MMP2 3844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.