Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 13/20 | 0.49 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799938 | 0.87 | GAA (0.44) | RORCTP53ALDH1A1NPSR1 | |
| SCHEMBL6800894 | 0.85 | HTR2A (0.46) | TAS2R14TP53 | |
| SCHEMBL6800301 | 0.84 | KMT2A (0.51) | ALDH1A1NPSR1 | |
| SCHEMBL6802180 | 0.81 | ALDH1A1 (0.44) | RORCALDH1A1NPSR1 | |
| SCHEMBL7339459 | 0.79 | KMT2A (0.54) | RORCTAS2R14MMP3ALDH1A1 | |
| SCHEMBL6800336 | 0.78 | NR1D1 (0.44) | RORCALDH1A1 | |
| SCHEMBL7342014 | 0.77 | ALDH1A1 (0.64) | TAS2R14MMP3ALDH1A1 | |
| SCHEMBL6799112 | 0.76 | RORC (0.45) | RORCALDH1A1 | |
| SCHEMBL6074818 | 0.75 | HCRTR2 (0.45) | ALDH1A1 | |
| SCHEMBL6802888 | 0.74 | NR1D1 (0.41) | RORCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040249172-A1 | Process for the preparationof prostaglandins and analogues thereof | RESOLUTION CHEMICALS LIMITED (GB) | 2004-12-09 | — | — | US | disclosed |
| US-6743787-B2 | FOR THERAPY OF METABOLIC DISORDERS MEDIATED BY INSULIN RESISTANCE OR HYPERGLYCEMIA IN A MAMMAL | WYETH | 2004-06-01 | — | — | US | disclosed |
| US-20030027795-A1 | N-(4-sulfonylaryl)cyclylamine-2-hydroxyethylamines as beta-3 adrenergic receptor agonists | WYETH | 2003-02-06 | — | — | US | disclosed |
| US-6444685-B1 | THERAPY FOR METABOLISM DISEASES; DIETETICS; ANTIDIABETIC AGENTS | WYETH | 2002-09-03 | — | — | US | disclosed |
| US-20020028797-A1 | N-(4-sulfonylaryl)Cyclylamine 2-hydroxyethylamines as beta-3 adrenergic receptor agonists | AMERICAN HOME PRODUCTS CORPORATION | 2002-03-07 | — | — | US | disclosed |
| WO-2002006274-A1 | N-(4-SULFONYLARYL)CYCLYLAMINE-2-HYDROXYETHYLAMINES AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040249172-A1 | Process for the preparationof prostaglandins and analogues thereof | PTGIS, PTGES, PTGES2 | RORC 3657/4885TAS2R14 4059/4885TP53 4192/4885 |
| US-20030027795-A1 | N-(4-sulfonylaryl)cyclylamine-2-hydroxyethylamines as beta-3 adrenergic receptor agonists | ADRB3, ADRB1, ADRB2 | RORC 1073/4885TAS2R14 2221/4885TP53 4712/4885 |
| US-20020028797-A1 | N-(4-sulfonylaryl)Cyclylamine 2-hydroxyethylamines as beta-3 adrenergic receptor agonists | ADRB3, ADRB1, ADRB2 | RORC 1140/4885TAS2R14 2416/4885TP53 4785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.