Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.45 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.45 |
| ▸ | SCN2B | O60939 | 4/20 | 0.45 |
| ▸ | SCN1A | P35498 | 4/20 | 0.45 |
| ▸ | SCN1B | Q07699 | 4/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL680758 | 0.85 | ALDH1A1 (0.51) | SCN3ASCN9ASCN2BSCN1ASCN1B | |
| SCHEMBL679956 | 0.84 | MAPK14 (0.55) | SCN3ASCN9ALPAR1LPAR5SCN2B | |
| SCHEMBL680561 | 0.81 | MMP13 (0.65) | SCN3ASCN9ABCL2L1MCL1HPGD | |
| SCHEMBL680466 | 0.80 | EZH2 (0.54) | SCN9ASCN2BSCN1ASCN1BSCN5A | |
| SCHEMBL679703 | 0.79 | SCN9A (0.49) | SCN3ASCN9ASCN2BSCN1ASCN1B | |
| SCHEMBL680791 | 0.78 | CA1 (0.61) | BCL2L1MCL1HPGDTSHRHTT | |
| SCHEMBL680289 | 0.78 | MCL1 (0.70) | SCN3ASCN9ABCL2L1MCL1HPGD | |
| SCHEMBL680496 | 0.78 | MMP13 (0.51) | SCN3ASCN9AP4HTMBCL2L1MCL1 | |
| SCHEMBL28377302 | 0.77 | LPAR1 (0.54) | LPAR1LPAR5HPGD | |
| SCHEMBL680286 | 0.77 | PGR (0.60) | SCN9ASCN2BSCN1ASCN1BSCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593427-B1 | SULFONAMIDE DERIVATIVES AS NAV1.7 INHIBITORS FOR THE TREATMENT OF PAIN | PFIZER LTD (GB) | 2014-12-24 | — | — | EP | disclosed |
| US-20120010207-A1 | Chemical Compounds | PFIZER LIMITED (GB) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010207-A1 | Chemical Compounds | SCN1A, SCN1B, SCN7A | SCN3A 8/4885SCN9A 13/4885LPAR1 776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.