Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.54 |
| ▸ | CTSS | P25774 | 5/20 | 0.47 |
| ▸ | CTSB | P07858 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | HSPA5 | P11021 | 5/20 | 0.44 |
| ▸ | HSPA2 | P54652 | 2/20 | 0.44 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.44 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6442766 | 0.91 | CTSL (0.65) | CTSLCTSSCTSBCTSKHSPA5 | |
| SCHEMBL6445846 | 0.87 | CTSL (0.56) | CTSLCTSSCTSBCTSKHSPA5 | |
| SCHEMBL6443541 | 0.86 | CTSL (0.51) | CTSLCTSSCTSBCTSKHSPA5 | |
| SCHEMBL6441980 | 0.84 | CTSL (0.49) | CTSLCTSSCTSBCTSKHSPA5 | |
| SCHEMBL6020789 | 0.84 | CTSL (0.65) | CTSLCTSSCTSBCTSKRAB9A | |
| SCHEMBL6021491 | 0.82 | CTSS (0.51) | CTSLCTSSCTSBCTSKLMNA | |
| SCHEMBL6443478 | 0.82 | CTSB (0.51) | CTSLCTSSCTSBCTSKHSPA5 | |
| SCHEMBL6019599 | 0.81 | CTSL (0.52) | CTSLCTSSCTSBCTSK | |
| SCHEMBL6020457 | 0.81 | CTSS (0.55) | CTSLCTSSCTSBCTSKKMT2A | |
| SCHEMBL6020511 | 0.81 | ALDH1A1 (0.49) | CTSLCTSSCTSBCTSKLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | claimed |