Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6477930 | 0.88 | MMP13 (0.48) | MMP13TRPA1EPHX2CDK2GSK3B | |
| SCHEMBL6819195 | 0.85 | LOXL2 (0.40) | MMP13TRPA1 | |
| SCHEMBL6814145 | 0.83 | TRPA1 (0.52) | MMP13TRPA1EPHX2PDE10AWDR5 | |
| SCHEMBL6819189 | 0.82 | KDM5A (0.37) | SCD | |
| SCHEMBL6476888 | 0.77 | RXRA (0.35) | — | |
| SCHEMBL6814148 | 0.74 | LOXL2 (0.40) | MMP13TRPA1EPHX2 | |
| SCHEMBL6487515 | 0.74 | MMP13 (0.46) | MMP13TRPA1EPHX2CDK2GSK3B | |
| SCHEMBL6822279 | 0.73 | TRPA1 (0.47) | MMP13TRPA1EPHX2PDE10AWDR5 | |
| SCHEMBL6814142 | 0.70 | KDM5A (0.35) | TRPA1SCD | |
| SCHEMBL6477648 | 0.70 | POLB (0.42) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014908-A1 | HETEROBICYLCIC METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | claimed |