Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 4/20 | 0.48 |
| ▸ | MDM4 | O15151 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6918963 | 0.91 | KDR (0.50) | MDM2MDM4MAPTCYP3A4TSHR | |
| SCHEMBL6820929 | 0.88 | KDR (0.46) | MDM2MDM4MAPTCYP3A4TSHR | |
| SCHEMBL6821059 | 0.87 | MAPT (0.48) | MAPTHSD17B10MEN1PPARGKMT2A | |
| SCHEMBL6821169 | 0.76 | KMT2A (0.52) | MAPTTSHRMEN1KMT2AKDM4E | |
| SCHEMBL6920117 | 0.76 | CA12 (0.48) | MAPTMEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL6820233 | 0.75 | CYP19A1 (0.59) | MAPTMEN1RECQLKMT2AKDM4E | |
| SCHEMBL6421393 | 0.75 | ACLY (0.53) | — | |
| SCHEMBL6926577 | 0.73 | MAPT (0.43) | MDM2MDM4MAPTCYP3A4TSHR | |
| SCHEMBL6821058 | 0.73 | PLA2G2A (0.57) | MAPTTSHRKMT2A | |
| SCHEMBL13295326 | 0.73 | KMT2A (0.46) | MAPTCYP3A4TSHRHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |