SCHEMBL6831087

SCHEMBL6831087

CSCCC(NS(=O)(=O)c1ccc(N)c2ccccc12)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.56
PKM P14618 1/20 0.56
PKLR P30613 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.54
GAA P10253 2/20 0.53
RECQL P46063 1/20 0.53
RAB9A P51151 1/20 0.51
KDM4E B2RXH2 2/20 0.49
POLB P06746 2/20 0.49
RXFP1 Q9HBX9 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
ALDH1A1 P00352 2/20 0.45
KEAP1 Q14145 1/20 0.45
FNTA P49354 1/20 0.44
FNTB P49356 1/20 0.44
CA2 P00918 2/20 0.44
CA1 P00915 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5149287 0.87 MMP9 (0.44) L3MBTL1
SCHEMBL1168298 0.85 MMP2 (0.46) CA2
SCHEMBL3863364 0.84 MMP9 (0.57) SMN1; SMN2L3MBTL1KEAP1
SCHEMBL5706285 0.84 MMP9 (0.57) SMN1; SMN2L3MBTL1KEAP1
SCHEMBL9670221 0.84 NSD2 (0.45) ALDH1A1
SCHEMBL7438340 0.83 LMNA (0.61) LMNAPKMPKLRSMN1; SMN2GAA
SCHEMBL3465132 0.83 MMP9 (0.60) L3MBTL1CA2CA1
SCHEMBL4137790 0.83 MMP9 (0.60) L3MBTL1CA2CA1
SCHEMBL6266412 0.83 PKLR (0.50) PKLR
SCHEMBL319322 0.82 MMP9 (0.61) CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240050572-A1 Polysorbate Mixtures Having Modified Fatty Acid Ester Distribution GENENTECH, INC. (US) 2024-02-15 US disclosed
US-11833206-B2 Polysorbate mixtures having modified fatty acid ester distribution GENENTECH, INC. (US) 2023-12-05 US disclosed
EP-4217003-A1 POLYSORBATE MIXTURES HAVING MODIFIED FATTY ACID ESTER DISTRIBUTION Genentech, Inc. (US) 2023-08-02 EP disclosed
CN-116528906-A Polysorbate blends with modified fatty acid ester distribution 基因泰克公司 2023-08-01 CN disclosed
US-20220111054-A1 POLYSORBATE MIXTURES HAVING MODIFIED FATTY ACID ESTER DISTRIBUTION GENENTECH, INC. (US) 2022-04-14 US disclosed
WO-2022066858-A1 POLYSORBATE MIXTURES HAVING MODIFIED FATTY ACID ESTER DISTRIBUTION GENENTECH, INC. (US) 2022-03-31 WO disclosed
US-6746663-B2 PHOTODYNAMIC DIAGNOSIS AND/OR TREATMENT FOR ANIMALS, PHOTOCHEMICAL CO., LTD. (JP) 2004-06-08 US disclosed
US-20030017112-A1 Used for photodynamic diagnosis and/or treatment for animals PHOTOCHEMICAL CO., LTD. (JP) 2003-01-23 US disclosed
EP-1148058-A1 PORPHYRIN COMPOUND Photochemical Co., Ltd. (JP) 2001-10-24 EP disclosed
US-5210029-A Cultivating Escherichia Coli with Iron and Magnesium Sources TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-05-11 US disclosed
EP-0200417-B1 PRODUCTION OF PROTEIN Takeda Chemical Industries, Ltd. (JP) 1992-10-21 EP disclosed
EP-0200417-A2 Production of protein Takeda Chemical Industries, Ltd. (JP) 1986-11-05 EP disclosed
US-4540548-A Method of detecting fluorescent materials and apparatus for their detection YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1985-09-10 US disclosed
US-4419452-A Method of detecting fluorescent materials and apparatus for their detection YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1983-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030017112-A1 Used for photodynamic diagnosis and/or treatment for animals PPOX, PPIF, VHL LMNA 3885/4885PKM 794/4885PKLR 795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.