Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 10/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.50 |
| ▸ | ICMT | O60725 | 1/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6833442 | 0.82 | ADRB2 (0.67) | ADRB2NQO2MTNR1AMTNR1B | |
| SCHEMBL194360 | 0.78 | MTNR1A (0.73) | AKR1C3NQO2MTNR1AMTNR1B | |
| SCHEMBL6938945 | 0.77 | MTNR1A (0.58) | AKR1C3NQO2MTNR1AMTNR1B | |
| SCHEMBL6921381 | 0.77 | MTNR1A (0.57) | NQO2MTNR1AMTNR1B | |
| SCHEMBL6921659 | 0.77 | HTR6 (0.68) | MTNR1A | |
| SCHEMBL14041516 | 0.77 | PLA2G2A (0.67) | PLA2G2AICMT | |
| SCHEMBL6944686 | 0.76 | MTNR1A (0.57) | NQO2MTNR1AMTNR1B | |
| SCHEMBL6939654 | 0.76 | MTNR1A (0.57) | AKR1C3NQO2MTNR1AMTNR1B | |
| SCHEMBL7963252 | 0.76 | PLA2G2A (1.00) | PLA2G2AICMTMTNR1AMTNR1B | |
| SCHEMBL7122186 | 0.75 | MTNR1A (0.55) | AKR1C3NQO2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004085392-A1 | MELATONIN DERIVATIVES AND THEIR USE FOR TREATING NEUROLOGICAL DYSFUNCTIONS | FAUST PHARMACEUTICALS (FR) | 2004-10-07 | — | — | WO | disclosed |
| WO-2004085395-A1 | MELATONIN DERIVATIVES AND THEIR USE FOR TREATING NEUROLOGICAL DYSFUNCTIONS | FAUST PHARMACEUTICALS (FR) | 2004-10-07 | — | — | WO | disclosed |