Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QRFPR | Q96P65 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6844864 | 0.91 | QRFPR (0.36) | QRFPR | |
| SCHEMBL6844872 | 0.80 | CA1 (0.36) | — | |
| SCHEMBL1649232 | 0.79 | SIGMAR1 (0.38) | QRFPRNPC1GAAMEN1KMT2A | |
| SCHEMBL6844927 | 0.78 | TARBP2 (0.32) | L3MBTL1 | |
| SCHEMBL1648272 | 0.74 | METAP2 (0.43) | QRFPRNPC1GAA | |
| SCHEMBL6844870 | 0.72 | EGFR (0.38) | — | |
| SCHEMBL6844919 | 0.72 | POLB (0.34) | KMT2AL3MBTL1 | |
| SCHEMBL6844867 | 0.71 | TSHR (0.32) | — | |
| SCHEMBL6844851 | 0.69 | ALDH1A1 (0.32) | L3MBTL1 | |
| SCHEMBL6844879 | 0.69 | POLB (0.36) | MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044506-A2 | SULPHONE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ZAFGEN CORPORATION (US) | 2011-04-14 | — | — | WO | disclosed |