SCHEMBL684763

SCHEMBL684763

[C-]#[N+]c1cc(C)c(NC(=O)c2cc(Cn3nnc(C(F)(F)F)n3)nn2-c2ccccc2Cl)c(C(=O)NC(C)C)c1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC16A3 O15427 4/20 0.31
SLC16A1 P53985 4/20 0.31
MCTS1 Q9ULC4 1/20 0.30
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL685551 0.92 IDH1 (0.32)
SCHEMBL684754 0.91 MEN1 (0.32) SLC16A3SLC16A1
SCHEMBL13085480 0.91 CNR2 (0.33) SLC16A3SLC16A1MCTS1CNR1CNR2
SCHEMBL685896 0.90 DHODH (0.32) SLC16A3SLC16A1MCTS1
SCHEMBL10150904 0.89 POLB (0.34) SLC16A3SLC16A1MCTS1CNR1CNR2
SCHEMBL10076313 0.88 SLC2A1 (0.34) SLC16A3SLC16A1MCTS1CNR1
SCHEMBL685492 0.87 DHODH (0.32)
SCHEMBL10072953 0.85 PDE4A (0.32)
SCHEMBL12033567 0.85 NPC1 (0.31) CNR1CNR2
SCHEMBL10150903 0.84 POLB (0.33) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170265470-A1 Anthranilamides in combination with fungicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-09-21 US disclosed
US-9700049-B2 Anthranilamides in combination with fungicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-07-11 US disclosed
US-20170156328-A1 USE OF AN ANTHRANILIC DIAMIDE DERIVATIVES WITH HETEROAROMATIC AND HETEROCYCLIC SUBSTITUENTS IN COMBINATION WITH A BIOLOGICALCONTROL AGENT BAYER INTELLECTUAL PROPERTY GMBH 2017-06-08 US disclosed
US-9572342-B2 Use of an anthranilic diamide derivatives with heteroaromatic and heterocyclic substituents in combination with a biologicalcontrol agent BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-02-21 US disclosed
US-9414595-B2 Use of anthranilic acid diamide derivatives for pest control in transgenic crops BAYER CROPSCIENCE AG (DE) 2016-08-16 US disclosed
US-20160128331-A1 ANTHRANILAMIDES IN COMBINATION WITH FUNGICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-05-12 US disclosed
US-9265255-B2 Anthranilamides in combination with fungicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-02-23 US disclosed
US-20160037775-A1 ACTIVE INGREDIENT COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-02-11 US disclosed
US-9198424-B2 Active ingredient combinations having insecticidal and acaricidal properties BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-12-01 US disclosed
US-20140329676-A1 USE OF ANTHRANILIC ACID DIAMIDE DERIVATIVES FOR PEST CONTROL IN TRANSGENIC CROPS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2014-11-06 US disclosed
US-8658570-B2 Use of anthranilamide derivatives for controlling insects and spider mites by drenching, soil mixing, furrow treatment, drip application, soil, stem or flower injection, in hydroponic systems, by planting hole treatment or dip application, floating or seedbox application or by treating seed, and also for enhancing the stress tolerance of plants to abiotic stress BAYER CROPSCIENCE AG (DE) 2014-02-25 US disclosed
US-20120022112-A1 USE OF ANTHRANILAMIDE DERIVATIVES FOR CONTROLLING INSECTS AND SPIDER MITES BY DRENCHING, SOIL MIXING, FURROW TREATMENT, DRIP APPLICATION, SOIL, STEM OR FLOWER INJECTION, IN HYDROPONIC SYSTEMS, BY PLANTING HOLE TREATMENT OR DIP APPLICATION, FLOATING OR SEEDBOX APPLICATION OR BY TREATING SEED, AND ALSO FOR ENHANCING THE STRESS TOLERANCE OF PLANTS TO ABIOTIC STRESS BAYER CROPSCIENCE AG (DE) 2012-01-26 US disclosed
US-20120010073-A1 Anthranilamides in combination with fungicides BAYER CROPSCIENCE AG (DE) 2012-01-12 US disclosed
US-20110311503-A1 Active ingredient combinations having insecticidal and acaricidal properties BAYER CROPSCIENCE AG (DE) 2011-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010073-A1 Anthranilamides in combination with fungicides AADAC, ANTXR2, CYP51A1 SLC16A3 4378/4885SLC16A1 4624/4885MCTS1 2363/4885
US-20120022112-A1 USE OF ANTHRANILAMIDE DERIVATIVES FOR CONTROLLING INSECTS AND SPIDER MITES BY DRENCHING, SOIL MIXING, FURROW TREATMENT, DRIP APPLICATION, SOIL, STEM OR FLOWER INJECTION, IN HYDROPONIC SYSTEMS, BY PLANTING HOLE TREATMENT OR DIP APPLICATION, FLOATING OR SEEDBOX APPLICATION OR BY TREATING SEED, AND ALSO FOR ENHANCING THE STRESS TOLERANCE OF PLANTS TO ABIOTIC STRESS CDY1; CDY1B, DHX9, DHX29 SLC16A3 4493/4885SLC16A1 4702/4885MCTS1 3954/4885
US-20140329676-A1 USE OF ANTHRANILIC ACID DIAMIDE DERIVATIVES FOR PEST CONTROL IN TRANSGENIC CROPS AADAC, DDT, QDPR SLC16A3 2681/4885SLC16A1 2725/4885MCTS1 1119/4885
US-20160128331-A1 ANTHRANILAMIDES IN COMBINATION WITH FUNGICIDES AADAC, ANTXR2, CYP51A1 SLC16A3 4378/4885SLC16A1 4624/4885MCTS1 2363/4885
US-20170265470-A1 Anthranilamides in combination with fungicides AADAC, ANTXR2, CYP51A1 SLC16A3 4378/4885SLC16A1 4624/4885MCTS1 2363/4885
US-20170156328-A1 USE OF AN ANTHRANILIC DIAMIDE DERIVATIVES WITH HETEROAROMATIC AND HETEROCYCLIC SUBSTITUENTS IN COMBINATION WITH A BIOLOGICALCONTROL AGENT CYC1, TPD52L2, DBF4 SLC16A3 4875/4885SLC16A1 4866/4885MCTS1 3786/4885
US-20110311503-A1 Active ingredient combinations having insecticidal and acaricidal properties ACHE, ACAT1, ACAT2 SLC16A3 4417/4885SLC16A1 4430/4885MCTS1 4605/4885
US-20160037775-A1 ACTIVE INGREDIENT COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES ACHE, ACAT1, ACAT2 SLC16A3 4417/4885SLC16A1 4430/4885MCTS1 4605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.