Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 1/20 | 0.42 |
| ▸ | HLCS | P50747 | 3/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL66669 | 0.91 | HINT1 (0.48) | HINT1HLCS | |
| SCHEMBL19982838 | 0.71 | HLCS (0.49) | HINT1HLCS | |
| SCHEMBL22897369 | 0.70 | HLCS (0.47) | HINT1HLCS | |
| SCHEMBL67110 | 0.70 | ADK (0.42) | — | |
| SCHEMBL19983263 | 0.70 | PLCD1 (0.43) | HLCSBTKTDP1 | |
| SCHEMBL22192980 | 0.69 | HLCS (0.46) | HINT1HLCSTDP1 | |
| SCHEMBL29592014 | 0.69 | PLCD1 (0.44) | HINT1HLCSBTKTDP1 | |
| SCHEMBL12450063 | 0.67 | ADK (0.48) | — | |
| SCHEMBL20129498 | 0.66 | FGF1 (0.51) | HINT1HLCSTDP1 | |
| SCHEMBL20129628 | 0.66 | FGF1 (0.51) | HINT1HLCSTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129106-B2 | Sequence-specific detection of methylation in biomolecules | Max-Planck-Geselischaft zur Forderung der Wissenschaften E.V. (DE) | 2012-03-06 | — | — | US | disclosed |
| US-20110165564-A1 | SEQUENCE-SPECIFIC DETECTION OF METHYLATION IN BIOMOLECULES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110165564-A1 | SEQUENCE-SPECIFIC DETECTION OF METHYLATION IN BIOMOLECULES | DNMT1, MAT2B, AHCY | HINT1 273/4885HLCS 593/4885BTK 3771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.