Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TACR3 | P29371 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NCF1 | P14598 | 2/20 | 0.46 |
| ▸ | CKS1B | P61024 | 1/20 | 0.46 |
| ▸ | SKP1 | P63208 | 1/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | SMO | Q99835 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6853013 | 0.84 | HRH3 (0.48) | FAAHALDH1A1KMT2AHRH3POLB | |
| SCHEMBL6854970 | 0.82 | KMT2A (0.50) | FAAHALDH1A1MAPTKMT2ANCF1 | |
| SCHEMBL6848678 | 0.81 | TACR2 (0.53) | FAAHTACR3HRH3NPSR1SLC2A1 | |
| SCHEMBL6848935 | 0.81 | SLC2A1 (0.44) | FAAHALDH1A1TACR3NCF1SLC2A1 | |
| SCHEMBL5442168 | 0.80 | PDE10A (0.43) | ADORA2AADORA1FAAHALDH1A1KMT2A | |
| SCHEMBL6857841 | 0.80 | FAAH (0.43) | ADORA2AADORA1FAAHALDH1A1MAPT | |
| SCHEMBL6853186 | 0.80 | LDHA (0.49) | ADORA2AADORA1FAAHTACR3KMT2A | |
| SCHEMBL6851740 | 0.79 | AKT1 (0.48) | FAAHALDH1A1PKM | |
| SCHEMBL6851670 | 0.79 | PDE10A (0.43) | FAAHALDH1A1MAPTTACR3NCF1 | |
| SCHEMBL27583471 | 0.78 | FAAH (0.44) | FAAHALDH1A1KMT2APKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6780875-B2 | RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; PSYCHOLOGICAL DISORDERS | SMITHKLINE BEECHAM S.P.A. (IT) | 2004-08-24 | — | — | US | disclosed |