Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6851310 | 0.93 | ADORA3 (0.39) | MAPTMAPK14L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL6858350 | 0.90 | ALDH1A1 (0.40) | MAPTTP53TSHRL3MBTL1NPC1 | |
| SCHEMBL6858344 | 0.83 | HTR7 (0.34) | ATMMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6855230 | 0.81 | FASN (0.34) | ALDH1A1 | |
| SCHEMBL6858360 | 0.80 | DHODH (0.34) | CYP3A4 | |
| SCHEMBL346736 | 0.78 | DHODH (0.36) | TP53NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL6857752 | 0.77 | DHODH (0.31) | — | |
| SCHEMBL7039428 | 0.74 | HTR1D (0.35) | — | |
| Phosphine SCHEMBL27595810 | 0.74 | ESR1 (0.53) | ESR1TP53TSHRL3MBTL1TDP1 | |
| SCHEMBL164293 | 0.70 | HTT (0.34) | MAPTTP53L3MBTL1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787557-B2 | 2,3-dimethyl-6-t-butyl-8-fluoro-4-hydroxyquinoline or ester derivatives; plant fungicides; Pyricularia | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-09-07 | — | — | US | claimed |
| US-6787557-B2 | 2,3-dimethyl-6-t-butyl-8-fluoro-4-hydroxyquinoline or ester derivatives; plant fungicides; Pyricularia | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-09-07 | — | — | US | disclosed |
| US-20030176459-A1 | Rice blast control agents | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2003-09-18 | — | — | US | disclosed |
| EP-1291344-A1 | RICE BLAST CONTROL AGENTS | MEIJI SEIKA KAISHA LTD. (JP) | 2003-03-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176459-A1 | Rice blast control agents | CNOT1, OSR1, RER1 | ESR1 4860/4885ATM 1079/4885MAPT 3187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.