SCHEMBL685597

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL685027	0.99	LTB4R (0.40)	LTB4RPLA2G2DALOX5PTGS2THRB
	SCHEMBL685759	0.83	ALDH1A1 (0.38)	MEN1ALDH1A1KMT2ATSHRMAPT
	SCHEMBL685608	0.83	SMPD1 (0.51)	THRBTHRAALDH1A1SMPD1
	SCHEMBL685900	0.81	SMPD1 (0.49)	THRBTHRAALDH1A1SMPD1
	SCHEMBL8702775	0.78	MTNR1A (0.50)	ALOX5MEN1ALDH1A1KMT2AHTR2A
	SCHEMBL685667	0.77	MEN1 (0.39)	ALOX5PTGS2THRBTHRAMEN1
	SCHEMBL27647108	0.77	THRA (0.46)	ALOX5THRBTHRAMEN1KMT2A
	SCHEMBL23891695	0.76	THRA (0.49)	ALOX5THRBTHRAMEN1ALDH1A1
	SCHEMBL12040081	0.76	TYR (0.50)	ALOX5THRBTHRAMEN1KMT2A
	SCHEMBL11767454	0.76	TYR (0.50)	ALOX5THRBTHRAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.