Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 4/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6864813 | 0.86 | MMP1 (0.38) | ALDH1A1KMT2AL3MBTL1MMP1MEP1B | |
| SCHEMBL6863775 | 0.85 | MMP1 (0.37) | ALDH1A1KMT2AL3MBTL1MMP1MEP1B | |
| SCHEMBL6864366 | 0.85 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1MMP1MEP1BCA2 | |
| SCHEMBL328390 | 0.79 | MMP1 (0.43) | MMP1MEP1BCA2MMP2MMP9 | |
| SCHEMBL6864101 | 0.78 | AHCY (0.38) | LTA4HKDM4E | |
| SCHEMBL6865493 | 0.77 | MMP3 (0.42) | ALDH1A1MEN1KMT2AL3MBTL1MMP1 | |
| SCHEMBL6864164 | 0.73 | MMP2 (0.33) | MEN1KMT2AATMLTA4HMMP1 | |
| SCHEMBL6852280 | 0.72 | BDKRB1 (0.40) | ALDH1A1MEN1KMT2AATMLTA4H | |
| SCHEMBL6865083 | 0.71 | MMP1 (0.48) | MMP1MEP1BCA2MMP2MMP9 | |
| SCHEMBL328407 | 0.70 | MMP1 (0.43) | MMP1MEP1BCA2MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041545-A1 | METHODS OF TREATING ANEURYSMAL DILATATION, BLOOD VESSEL WALL WEAKNESS AND SPECIFICALLY ABDOMINAL AORTIC AND THORACIC ANEURYSM USING MATRIX METALLOPROTEASE-2 INHIBITORS | SYMPHONY EVOLUTION, INC. (US) | 2011-04-07 | — | — | WO | disclosed |