Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 13/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10067173 | 0.83 | MMP3 (0.49) | AHCYMMP3LTA4HPTGS2 | |
| SCHEMBL328413 | 0.82 | MMP3 (0.51) | AHCYMMP3HRH3 | |
| SCHEMBL6864366 | 0.81 | ALDH1A1 (0.34) | MMP3 | |
| SCHEMBL6864164 | 0.80 | MMP2 (0.33) | MMP3LTA4H | |
| SCHEMBL6865493 | 0.79 | MMP3 (0.42) | MMP3 | |
| SCHEMBL6863772 | 0.78 | ALDH1A1 (0.35) | LTA4HKDM4E | |
| SCHEMBL6864813 | 0.78 | MMP1 (0.38) | MMP3 | |
| SCHEMBL6863775 | 0.78 | MMP1 (0.37) | MMP3 | |
| SCHEMBL6852386 | 0.75 | MMP3 (0.38) | AHCYMMP3LTA4HPTGS2HRH3 | |
| SCHEMBL6864356 | 0.74 | MEN1 (0.37) | MMP3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041545-A1 | METHODS OF TREATING ANEURYSMAL DILATATION, BLOOD VESSEL WALL WEAKNESS AND SPECIFICALLY ABDOMINAL AORTIC AND THORACIC ANEURYSM USING MATRIX METALLOPROTEASE-2 INHIBITORS | SYMPHONY EVOLUTION, INC. (US) | 2011-04-07 | — | — | WO | disclosed |