Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15535068 | 0.79 | ALDH1A1 (0.41) | ALDH1A1TSHRTGFBR1MAPK1TDP1 | |
| SCHEMBL316224 | 0.78 | TGFBR1 (0.41) | ALDH1A1TSHRTGFBR1MAPK1TDP1 | |
| SCHEMBL19880119 | 0.78 | ZDHHC20 (0.50) | ALDH1A1TSHRTGFBR1ZDHHC20ZDHHC2 | |
| SCHEMBL17239830 | 0.78 | ZDHHC20 (0.50) | ALDH1A1TSHRTGFBR1ZDHHC20ZDHHC2 | |
| SCHEMBL13205118 | 0.77 | PLA2G2A (0.36) | ALDH1A1TGFBR1MAPK1TDP1PLA2G2A | |
| SCHEMBL907324 | 0.77 | PLA2G2A (0.48) | ALDH1A1TGFBR1PLA2G2A | |
| SCHEMBL23031131 | 0.76 | TSHR (0.55) | ALDH1A1TSHR | |
| SCHEMBL2858627 | 0.75 | ALDH1A1 (0.34) | ALDH1A1TSHRTGFBR1ZDHHC20ZDHHC2 | |
| SCHEMBL6402194 | 0.75 | TDP1 (0.40) | ALDH1A1TGFBR1MAPK1TDP1PLA2G2A | |
| SCHEMBL10386869 | 0.74 | ZDHHC20 (0.56) | ALDH1A1TSHRZDHHC20ZDHHC2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6818718-B2 | IMPROVED SEPARATION OF PROTEINS, ENZYMES, PEPTIDES, OLIGONUCLEOTIDES, POLYNUCLEOTIDES, AND CARBOHYDRATES | THE UNIVERSITY OF MELBOURNE (AU) | 2004-11-16 | — | — | US | disclosed |
| US-20010020079-A1 | Electrophoresis gels and cross-linking agents for their preparation | THE UNIVERSITY OF MELBOURNE | 2001-09-06 | — | — | US | disclosed |
| US-6197906-B1 | ASSYMETRIC AGENTS SUCH AS (2-METHACRYLOYLOXYETHYL)ACRYLAMIDE, (2-ACRYLOYLOXYETHYL)METHACRYLAMIDE, AND (N-METHYL-N-ACRYLOYLAMINO)ETHYL METHACRYLATE | THE UNIVERSITY OF MELBOURNE (AU) | 2001-03-06 | — | — | US | disclosed |
| EP-0920412-A4 | ELECTROPHORESIS GELS AND CROSS-LINKING AGENTS FOR THEIR PREPARATION | UNIV MELBOURNE (AU) | 2000-08-02 | — | — | EP | disclosed |
| EP-0920412-A1 | ELECTROPHORESIS GELS AND CROSS-LINKING AGENTS FOR THEIR PREPARATION | THE UNIVERSITY OF MELBOURNE (AU) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998001419-A1 | ELECTROPHORESIS GELS AND CROSS-LINKING AGENTS FOR THEIR PREPARATION | THE UNIVERSITY OF MELBOURNE (AU) | 1998-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010020079-A1 | Electrophoresis gels and cross-linking agents for their preparation | MACF1, ZYX, F12 | ALDH1A1 794/4885TSHR 4643/4885TGFBR1 3325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.