Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | TDO2 | P48775 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6882198 | 0.92 | CYP11B1 (0.41) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL11410727 | 0.87 | HTR2A (0.42) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL8971859 | 0.84 | CYP11B2 (0.48) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL24495510 | 0.82 | SLC6A2 (0.44) | MEN1KMT2ACYP11B1CYP11B2IDO1 | |
| SCHEMBL11034392 | 0.82 | MEN1 (0.40) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL3691459 | 0.82 | MEN1 (0.40) | MEN1KMT2ACYP11B1CYP11B2RAB9A | |
| SCHEMBL24216109 | 0.82 | KDM1A (0.53) | MEN1KMT2ACYP11B1CYP11B2RAB9A | |
| SCHEMBL8493393 | 0.82 | MEN1 (0.40) | MEN1KMT2ACYP11B1CYP11B2RAB9A | |
| SCHEMBL21140944 | 0.82 | HTR2A (0.46) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL3711765 | 0.82 | ABCC9 (0.44) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3196189-B1 | METHOD FOR PRODUCING 2-AMINO-SUBSTITUTED BENZALDEHYDE COMPOUND | NIPPON SODA CO (JP) | 2020-09-23 | — | — | EP | disclosed |
| CN-106573874-B | The method for manufacturing 2- amino substituted benzoyl aldehyde compounds | 日本曹达株式会社 | 2018-06-12 | — | — | CN | disclosed |
| US-20170226046-A1 | METHOD FOR PRODUCING 2-AMINO-SUBSTITUTED BENZALDEHYDE COMPOUND | NIPPON SODA CO., LTD. (JP) | 2017-08-10 | — | — | US | disclosed |
| US-20170226046-A1 | METHOD FOR PRODUCING 2-AMINO-SUBSTITUTED BENZALDEHYDE COMPOUND | NIPPON SODA CO., LTD. (JP) | 2017-08-10 | — | — | US | disclosed |
| US-20170226046-A1 | METHOD FOR PRODUCING 2-AMINO-SUBSTITUTED BENZALDEHYDE COMPOUND | NIPPON SODA CO., LTD. (JP) | 2017-08-10 | — | — | US | disclosed |
| EP-3196189-A1 | METHOD FOR PRODUCING 2-AMINO-SUBSTITUTED BENZALDEHYDE COMPOUND | Nippon Soda Co., Ltd. (JP) | 2017-07-26 | — | — | EP | disclosed |
| CN-106573874-A | Method for producing 2-amino-substituted benzaldehyde compound | 日本曹达株式会社 | 2017-04-19 | — | — | CN | disclosed |
| US-20120202837-A1 | SPIROCYCLIC PIPERIDINE DERIVATIVES USEFUL AS RENIN INHIBITORS | MERCK CANADA INC. (CA) | 2012-08-09 | — | — | US | disclosed |
| US-20120202837-A1 | SPIROCYCLIC PIPERIDINE DERIVATIVES USEFUL AS RENIN INHIBITORS | MERCK CANADA INC. (CA) | 2012-08-09 | — | — | US | disclosed |
| WO-2011057382-A1 | SPIROCYCLIC PIPERIDINE DERIVATIVES USEFUL AS RENIN INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2011-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202837-A1 | SPIROCYCLIC PIPERIDINE DERIVATIVES USEFUL AS RENIN INHIBITORS | REN, AGTR1, AGTR2 | MEN1 3768/4885KMT2A 4013/4885HTR2A 3842/4885 |
| US-20170226046-A1 | METHOD FOR PRODUCING 2-AMINO-SUBSTITUTED BENZALDEHYDE COMPOUND | AZI2, DAO, ALKBH2 | MEN1 2892/4885KMT2A 297/4885HTR2A 188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.