SCHEMBL6869156

SCHEMBL6869156

O=C(O)C(Cc1ccc(I)cc1)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 2/20 0.57
FPR2 P25090 3/20 0.46
MDM2 Q00987 1/20 0.45
CYP1A2 P05177 2/20 0.45
TPMT P51580 1/20 0.44
CYP2D6 P10635 1/20 0.44
SLC7A5 Q01650 1/20 0.44
LMNA P02545 1/20 0.42
ALB P02768 1/20 0.42
ESR1 P03372 1/20 0.42
ALOX5 P09917 1/20 0.42
RARB P10826 1/20 0.42
CYP2C9 P11712 1/20 0.42
ADRB3 P13945 1/20 0.42
NFKB1 P19838 1/20 0.42
PTGS1 P23219 1/20 0.42
HTR2A P28223 1/20 0.42
PTGS2 P35354 1/20 0.42
AKR1C3 P42330 1/20 0.42
NR1I3 Q14994 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30877184 0.88 LDHA (0.68) LDHAMDM2CYP1A2SLC7A5LMNA
SCHEMBL17161259 0.83 KDM6B (0.56) LDHAFPR2CYP1A2TPMTCYP2D6
SCHEMBL17518184 0.83 CYP1A2 (0.46) LDHAFPR2MDM2CYP1A2CYP2D6
SCHEMBL31649452 0.83 KDM6B (0.56) LDHAFPR2CYP1A2TPMTCYP2D6
Iodofalan SCHEMBL44620 0.81 SLC7A5 (0.69) CYP1A2SLC7A5LMNANFKB1PTGS1
SCHEMBL457465 0.81 TBXAS1 (0.51) FPR2CYP1A2CYP2D6LMNAALB
Iodofalan SCHEMBL44619 0.81 SLC7A5 (0.69) CYP1A2SLC7A5LMNANFKB1PTGS1
Iodofalan SCHEMBL44618 0.81 SLC7A5 (0.69) CYP1A2SLC7A5LMNANFKB1PTGS1
SCHEMBL12639935 0.81 TBXAS1 (0.51) FPR2CYP1A2CYP2D6LMNAALB
SCHEMBL9910745 0.81 TBXAS1 (0.51) FPR2CYP1A2CYP2D6LMNAALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12612421-B2 Method for producing 4-borono-L-phenylalanine and intermediate thereof STELLA PHARMA CORPORATION (JP) 2026-04-28 US disclosed
US-20230416280-A1 METHOD FOR PRODUCING 4-BORONO-L-PHENYLALANINE AND INTERMEDIATE THEREOF STELLA PHARMA CORPORATION (JP) 2023-12-28 US disclosed
EP-2975022-B1 NOVEL HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF FUJIFILM TOYAMA CHEMICAL CO LTD (JP) 2019-05-08 EP disclosed
US-9862676-B2 Hydroxamic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2018-01-09 US disclosed
US-20160039751-A1 NOVEL HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2016-02-11 US disclosed
EP-2975022-A1 NOVEL HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF Toyama Chemical Co., Ltd. (JP) 2016-01-20 EP disclosed
US-20120309674-A1 PSEUDODIPEPTIDES AS MMP INHIBITORS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENE ALT (FR) 2012-12-06 US disclosed
US-20120309674-A1 PSEUDODIPEPTIDES AS MMP INHIBITORS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENE ALT (FR) 2012-12-06 US disclosed
US-20120309674-A1 PSEUDODIPEPTIDES AS MMP INHIBITORS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENE ALT (FR) 2012-12-06 US disclosed
WO-2011023864-A1 PSEUDODIPEPTIDES AS MMP INHIBITORS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2011-03-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230416280-A1 METHOD FOR PRODUCING 4-BORONO-L-PHENYLALANINE AND INTERMEDIATE THEREOF PAH, BCAT2, BCAT1 LDHA 1963/4885FPR2 2193/4885MDM2 3931/4885
US-20160039751-A1 NOVEL HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF H1-0, H1-2, HDAC1 LDHA 162/4885FPR2 1112/4885MDM2 4520/4885
US-12612421-B2 Method for producing 4-borono-L-phenylalanine and intermediate thereof BCAT2, BCAT1, CLIC4 LDHA 338/4885FPR2 1793/4885MDM2 4501/4885
US-20120309674-A1 PSEUDODIPEPTIDES AS MMP INHIBITORS MMP3, MMP11, TIMP3 LDHA 3096/4885FPR2 840/4885MDM2 2634/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.