Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5595638 | 0.86 | ALDH1A1 (0.33) | ALDH1A1POLBHTTSMN1; SMN2ABHD6 | |
| SCHEMBL5713338 | 0.82 | L3MBTL1 (0.38) | ALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL3664525 | 0.81 | L3MBTL1 (0.40) | ALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL3636033 | 0.78 | CA2 (0.35) | ALDH1A1POLBHTTSMN1; SMN2ABHD6 | |
| SCHEMBL4440022 | 0.77 | DPP4 (0.39) | DPP8ALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL13176061 | 0.76 | DPP8 (0.40) | DPP8ALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL8815940 | 0.76 | ALDH1A1 (0.41) | ALDH1A1POLBHTTSMN1; SMN2CYP3A4 | |
| SCHEMBL4767291 | 0.74 | CTSK (0.38) | DPP8ALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL6622774 | 0.74 | ALOX15 (0.37) | ALDH1A1POLBHTTSMN1; SMN2ABHD6 | |
| SCHEMBL3664088 | 0.74 | GAA (0.35) | DPP8ALDH1A1POLBHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444203-A1 | CANNABINOID RECEPTOR LIGANDS | Schering Corporation (US) | 2004-08-11 | — | — | EP | disclosed |
| WO-2003042174-A1 | CANNABINOID RECEPTOR LIGANDS | SCHERING CORPORATION (US) | 2003-05-22 | — | — | WO | disclosed |