Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5713338 | 0.82 | L3MBTL1 (0.38) | ALDH1A1SMN1; SMN2POLBHTTMEN1 | |
| SCHEMBL3664525 | 0.81 | L3MBTL1 (0.40) | ALDH1A1SMN1; SMN2POLBHTTMEN1 | |
| SCHEMBL3636033 | 0.78 | CA2 (0.35) | ALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL4440022 | 0.77 | DPP4 (0.39) | ALDH1A1SMN1; SMN2POLBHTTTDP1 | |
| SCHEMBL5595638 | 0.77 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2POLBHTTMEN1 | |
| SCHEMBL6622774 | 0.77 | ALOX15 (0.37) | ALDH1A1SMN1; SMN2POLBHTTKDM4E | |
| SCHEMBL6880128 | 0.76 | DPP8 (0.35) | ALDH1A1SMN1; SMN2POLBHTTCYP3A4 | |
| SCHEMBL5972477 | 0.75 | KMT2A (0.51) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL4767291 | 0.74 | CTSK (0.38) | ALDH1A1SMN1; SMN2POLBHTTL3MBTL1 | |
| SCHEMBL3664088 | 0.74 | GAA (0.35) | ALDH1A1SMN1; SMN2POLBHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997022611-A1 | CEPHALOSPORIN DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-06-26 | — | — | WO | disclosed |