Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | LGMN | Q99538 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28832445 | 0.89 | TRPV4 (0.44) | TRPV4KCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL10123500 | 0.84 | TRPV4 (0.41) | TRPV4KCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL12349893 | 0.82 | KCNH2 (0.39) | TRPV4KCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL13335207 | 0.82 | KCNH2 (0.39) | TRPV4KCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL12464357 | 0.82 | KCNH2 (0.41) | TRPV4KCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL17938305 | 0.81 | KCNH2 (0.38) | TRPV4KCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL27969035 | 0.80 | TRPV4 (0.40) | TRPV4KCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL12425101 | 0.80 | KCNH2 (0.37) | TRPV4KCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL16622003 | 0.79 | KCNH2 (0.36) | TRPV4KCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL17938310 | 0.79 | KCNH2 (0.39) | TRPV4KCNH2MAP4K4PIK3CAMINK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3120701-B1 | STABLE SULFOXIMINE-INSECTICIDE COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2019-08-28 | — | — | EP | disclosed |
| EP-3120701-A1 | STABLE SULFOXIMINE-INSECTICIDE COMPOSITIONS | Dow AgroSciences LLC (US) | 2017-01-25 | — | — | EP | disclosed |
| EP-2268615-B1 | PESTICIDES | DOW AGROSCIENCES LLC (US) | 2016-08-17 | — | — | EP | disclosed |
| EP-2268615-B1 | PESTICIDES | DOW AGROSCIENCES LLC (US) | 2016-08-17 | — | — | EP | disclosed |
| US-20160212997-A1 | AGRICULTURAL CHEMICALS | REDAG CROP PROT LTD (GB) | 2016-07-28 | — | — | US | disclosed |
| EP-2369921-B1 | STABLE SULFOXIMINE-INSECTICIDE COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-07-27 | — | — | EP | disclosed |
| EP-2369935-B1 | STABLE INSECTICIDE COMPOSITIONS AND METHODS FOR PRODUCING SAME | DOW AGROSCIENCES LLC (US) | 2016-07-27 | — | — | EP | disclosed |
| EP-3046418-A2 | AGRICULTURAL CHEMICALS | Redag Crop Protection Ltd (GB) | 2016-07-27 | — | — | EP | disclosed |
| US-9125412-B2 | Stable insecticide compositions and methods for producing same | DOW AGROSCIENCES LLC (US) | 2015-09-08 | — | — | US | disclosed |
| US-9125412-B2 | Stable insecticide compositions and methods for producing same | DOW AGROSCIENCES LLC (US) | 2015-09-08 | — | — | US | disclosed |
| US-20090029863-A1 | PESTICIDES AND USES THEREOF | DOW AGROSCIENCES LLC (US) | 2009-01-29 | — | — | US | disclosed |
| US-20090023782-A1 | INCREASING PLANT VIGOR | DOW AGROSCIENCES LLC (IN) | 2009-01-22 | — | — | US | disclosed |
| US-20090023782-A1 | INCREASING PLANT VIGOR | DOW AGROSCIENCES LLC (IN) | 2009-01-22 | — | — | US | disclosed |
| US-20090023782-A1 | INCREASING PLANT VIGOR | DOW AGROSCIENCES LLC (IN) | 2009-01-22 | — | — | US | disclosed |
| EP-1989184-A2 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)ALKYL SULFOXIMINES | Dow AgroSciences LLC (US) | 2008-11-12 | — | — | EP | disclosed |
| US-20070203191-A1 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines | CORTEVA AGRISCIENCE LLC | 2007-08-30 | — | — | US | disclosed |
| US-20070203191-A1 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines | CORTEVA AGRISCIENCE LLC | 2007-08-30 | — | — | US | disclosed |
| US-20070203191-A1 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines | CORTEVA AGRISCIENCE LLC | 2007-08-30 | — | — | US | disclosed |
| WO-2007095229-A2 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)ALKYL SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2007-08-23 | — | — | WO | disclosed |
| WO-2007095229-A2 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)ALKYL SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2007-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023782-A1 | INCREASING PLANT VIGOR | HDLBP, VPS4B, VPS28 | TRPV4 3503/4885KCNH2 1716/4885MAP4K4 463/4885 |
| US-20090029863-A1 | PESTICIDES AND USES THEREOF | ACHE, DDT, BCHE | TRPV4 1173/4885KCNH2 532/4885MAP4K4 4394/4885 |
| US-20070203191-A1 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines | NPEPPS, PRDX6, HDHD5 | TRPV4 1575/4885KCNH2 414/4885MAP4K4 3433/4885 |
| US-20160212997-A1 | AGRICULTURAL CHEMICALS | CYP3A7, CYP4X1, CYP2A7 | TRPV4 1185/4885KCNH2 1067/4885MAP4K4 621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.