Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 6/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6894924 | 0.82 | KDM4E (0.43) | ANPEPKDM4ELMNAADRA2AADRA2C | |
| SCHEMBL6895263 | 0.82 | KDM4E (0.43) | ANPEPKDM4ELMNAADRA2AADRA2C | |
| SCHEMBL289245 | 0.76 | APAF1 (0.53) | ANPEPKDM4ELMNAADRA2AALDH1A1 | |
| SCHEMBL289244 | 0.76 | APAF1 (0.53) | ANPEPKDM4ELMNAADRA2AALDH1A1 | |
| SCHEMBL6895745 | 0.75 | LMNA (0.47) | KDM4ELMNAADRA2AADRA2CHIF1A | |
| SCHEMBL6895074 | 0.74 | HPGD (0.44) | ANPEPKDM4ELMNAADRA2AADRA2C | |
| SCHEMBL6890899 | 0.74 | AOC3 (0.36) | KDM4ELMNAADRA2AADRA2CHIF1A | |
| SCHEMBL6894568 | 0.74 | CYP3A4 (0.44) | ANPEPKDM4ELMNAADRA2AADRA2C | |
| SCHEMBL6889436 | 0.72 | SIGMAR1 (0.49) | ANPEPLMNAADRA2AHIF1AALDH1A1 | |
| SCHEMBL6896045 | 0.72 | ALDH1A1 (0.49) | ANPEPKDM4ELMNAADRA2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |