Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 2/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6895074 | 0.86 | HPGD (0.44) | LMNAALDH1A1 | |
| SCHEMBL6896045 | 0.83 | ALDH1A1 (0.49) | LMNAALDH1A1NPSR1GAA | |
| SCHEMBL6890899 | 0.82 | AOC3 (0.36) | LMNAALDH1A1NPSR1 | |
| SCHEMBL6894568 | 0.80 | CYP3A4 (0.44) | ADRA1AHTR1ADRD2DRD3LMNA | |
| SCHEMBL6889436 | 0.78 | SIGMAR1 (0.49) | SIGMAR1ADRA1AHTR1ALMNAADRB2 | |
| SCHEMBL6891363 | 0.76 | KMT2A (0.55) | SIGMAR1ADRB2ADRB3ALDH1A1GAA | |
| SCHEMBL6894924 | 0.76 | KDM4E (0.43) | L3MBTL1LMNAALDH1A1 | |
| SCHEMBL6895263 | 0.76 | KDM4E (0.43) | L3MBTL1LMNACYP2D6ALDH1A1 | |
| SCHEMBL6887458 | 0.76 | SIGMAR1 (0.51) | SIGMAR1CYP2D6 | |
| SCHEMBL10990052 | 0.76 | SIGMAR1 (0.61) | SIGMAR1HTR1BHTR1DADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |