Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5585671 | 0.84 | SLC6A2 (0.46) | SLC6A2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6196123 | 0.78 | SLC6A2 (0.55) | SLC6A2ALDH1A1MEN1KMT2ASLC6A4 | |
| SCHEMBL5585853 | 0.71 | CHRNB2 (0.49) | SLC6A2CHRNB2CHRNA4HTR7 | |
| SCHEMBL238407 | 0.69 | HTR7 (0.53) | SLC6A2ALDH1A1KDM4ECHRNB2CHRNA4 | |
| SCHEMBL26724558 | 0.68 | LMNA (0.60) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL12744970 | 0.67 | CHRNB2 (0.75) | CHRNB2CHRNA4 | |
| SCHEMBL5585706 | 0.67 | LTA4H (0.50) | ALDH1A1MEN1KMT2ACHRNB2CHRNA4 | |
| SCHEMBL30880799 | 0.66 | SLC6A2 (0.36) | SLC6A2ALDH1A1MEN1KMT2ACHRNB2 | |
| SCHEMBL5585616 | 0.65 | KDM4E (0.47) | SLC6A2ALDH1A1KDM4EHTR7SMN1; SMN2 | |
| SCHEMBL12744959 | 0.65 | LTA4H (0.58) | ALDH1A1MEN1KMT2ACHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040029888-A1 | Novel compounds, their use and preparation | PROXIMAGEN NEUROSCIENCE PLC (GB) | 2004-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029888-A1 | Novel compounds, their use and preparation | TPH1, TPH2, HTR1A | SLC6A2 23/4885ALDH1A1 445/4885KDM4E 3125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.