Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13306871 | 0.84 | — | — | |
| SCHEMBL12138136 | 0.75 | KMT2A (0.39) | KMT2A | |
| SCHEMBL10227000 | 0.75 | KMT2A (0.54) | KMT2A | |
| SCHEMBL19059374 | 0.73 | — | — | |
| SCHEMBL13306799 | 0.73 | — | — | |
| SCHEMBL24417705 | 0.73 | ALDH1A1 (0.43) | KMT2A | |
| SCHEMBL13306883 | 0.73 | PTGS2 (0.31) | — | |
| SCHEMBL23603564 | 0.73 | KMT2A (0.33) | KMT2A | |
| SCHEMBL15889702 | 0.70 | APEX1 (0.33) | KMT2A | |
| SCHEMBL13306767 | 0.70 | ALDH1A1 (0.31) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210395256-A1 | TYROSINE KINASE INHIBITORS, COMPOSITIONS AND METHODS THERE OF | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2021-12-23 | — | — | US | disclosed |
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | EDIGENE BIOTECHNOLOGY, INC. (CN) | 2021-07-22 | — | — | US | disclosed |
| US-10358427-B2 | Modulators of indoleamine 2,3-dioxygenase | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-07-23 | — | — | US | disclosed |
| US-9522914-B2 | Azole derivative | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2016-12-20 | — | — | US | disclosed |
| US-9216970-B2 | Dual-acting thiophene, pyrrole, thiazole and furan antihypertensive agents | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2015-12-22 | — | — | US | disclosed |
| US-9115149-B2 | Heterocyclic compounds as inhibitors of fatty acid biosysnthesis for bacterial infections | VITAS PHARMA RESEARCH PRIVATE LIMITED (IN) | 2015-08-25 | — | — | US | disclosed |
| US-20150105392-A1 | DUAL-ACTING THIOPHENE, PYRROLE, THIAZOLE AND FURAN ANTIHYPERTENSIVE AGENTS | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2015-04-16 | — | — | US | disclosed |
| US-8946233-B2 | Dual-acting thiophene, pyrrole, thiazole and furan antihypertensive agents | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2015-02-03 | — | — | US | disclosed |
| US-20140275006-A1 | AZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2014-09-18 | — | — | US | disclosed |
| US-20140249170-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF FATTY ACID BIOSYSNTHESIS FOR BACTERIAL INFECTIONS | KUMAR, AJAY, DR. (GB) | 2014-09-04 | — | — | US | disclosed |
| US-20140135333-A1 | DUAL-ACTING THIOPHENE, PYRROLE, THIAZOLE AND FURAN ANTIHYPERTENSIVE AGENTS | THERAVANCE, INC. (US) | 2014-05-15 | — | — | US | disclosed |
| US-8664227-B2 | Dual-acting thiophene, pyrrole, thiazole and furan antihypertensive agents | THERAVANCE, INC. (US) | 2014-03-04 | — | — | US | disclosed |
| US-20130267539-A1 | DUAL-ACTING THIOPHENE, PYRROLE, THIAZOLE AND FURAN ANTIHYPERTENSIVE AGENTS | THERAVANCE, INC. (US) | 2013-10-10 | — | — | US | disclosed |
| US-8481549-B2 | Dual-acting thiophene, pyrrole, thiazole and furan antihypertensive agents | THERAVANCE, INC. (US) | 2013-07-09 | — | — | US | disclosed |
| US-20110178101-A1 | DUAL-ACTING THIOPHENE, PYRROLE, THIAZOLE AND FURAN ANTIHYPERTENSIVE AGENTS | THERAVANCE BIOPHARMA R&D IP, LLC | 2011-07-21 | — | — | US | disclosed |
| US-7300639-B2 | Process for removing metals from liquids | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210395256-A1 | TYROSINE KINASE INHIBITORS, COMPOSITIONS AND METHODS THERE OF | ABL1, LCK, ERBB2 | KMT2A 1747/4885 |
| US-20110178101-A1 | DUAL-ACTING THIOPHENE, PYRROLE, THIAZOLE AND FURAN ANTIHYPERTENSIVE AGENTS | REN, AGTR1, AGTR2 | KMT2A 3201/4885 |
| US-20140135333-A1 | DUAL-ACTING THIOPHENE, PYRROLE, THIAZOLE AND FURAN ANTIHYPERTENSIVE AGENTS | REN, AGTR1, AGTR2 | KMT2A 3201/4885 |
| US-20140275006-A1 | AZOLE DERIVATIVE | AVPR1B, AVPR1A, AVPR2 | KMT2A 1836/4885 |
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | AHR, ARNT, ARSA | KMT2A 503/4885 |
| US-10358427-B2 | Modulators of indoleamine 2,3-dioxygenase | IDO1, IDO2, INMT | KMT2A 925/4885 |
| US-20140249170-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF FATTY ACID BIOSYSNTHESIS FOR BACTERIAL INFECTIONS | FASN, DBI, FAAH | KMT2A 4522/4885 |
| US-20130267539-A1 | DUAL-ACTING THIOPHENE, PYRROLE, THIAZOLE AND FURAN ANTIHYPERTENSIVE AGENTS | REN, AGTR1, AGTR2 | KMT2A 3201/4885 |
| US-20150105392-A1 | DUAL-ACTING THIOPHENE, PYRROLE, THIAZOLE AND FURAN ANTIHYPERTENSIVE AGENTS | REN, AGTR1, AGTR2 | KMT2A 3201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.