Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6902406 | 0.89 | TGFBR1 (0.39) | NPC1RAB9ATDP1MEN1KMT2A | |
| SCHEMBL6903067 | 0.86 | NPC1 (0.34) | CYP1A2CYP2D6CYP2C9CYP2C19NPC1 | |
| SCHEMBL6902617 | 0.86 | ALOX5AP (0.30) | NR3C1 | |
| Hydrochloric Acid SCHEMBL6904046 | 0.85 | ALDH1A1 (0.33) | ALDH1A1LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6903610 | 0.83 | PKM (0.40) | ALDH1A1LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6895367 | 0.83 | TGFBR1 (0.38) | ALDH1A1LMNACYP1A2NPC1HPGD | |
| SCHEMBL6895444 | 0.83 | CYP1A2 (0.34) | CYP1A2CYP2D6CYP2C9CYP2C19CYP19A1 | |
| SCHEMBL6901820 | 0.81 | PKM (0.32) | ALDH1A1LMNANPC1HPGDRAB9A | |
| SCHEMBL6902437 | 0.81 | BRS3 (0.38) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6900002 | 0.81 | TRPV1 (0.39) | ALDH1A1NPC1HPGDRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033371-B1 | Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2004-01-28 | — | — | EP | claimed |