Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F12 | P00748 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6895444 | 0.92 | CYP1A2 (0.34) | CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL6902437 | 0.90 | BRS3 (0.38) | NPC1MAPTRAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL6904267 | 0.88 | CYP1A2 (0.36) | NPC1MAPTRAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL6903610 | 0.88 | PKM (0.40) | NPC1MAPTRAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL6895367 | 0.88 | TGFBR1 (0.38) | NPC1MAPTRAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL6901820 | 0.86 | PKM (0.32) | NPC1MAPTRAB9ASMN1; SMN2GRM5 | |
| SCHEMBL6901735 | 0.86 | ALDH1A1 (0.33) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL6902406 | 0.85 | TGFBR1 (0.39) | NPC1MAPTRAB9ATSHRTDP1 | |
| SCHEMBL6900002 | 0.85 | TRPV1 (0.39) | NPC1MAPTRAB9AS1PR1KDM4E | |
| SCHEMBL6901825 | 0.84 | ALDH1A1 (0.34) | NPC1MAPTRAB9ASMN1; SMN2EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033371-B1 | Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2004-01-28 | — | — | EP | claimed |