Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | CCR1 | P32246 | 2/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | CCR8 | P51685 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6903610 | 0.90 | PKM (0.40) | TGFBR1GRM5SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6903067 | 0.88 | NPC1 (0.34) | GRM5SMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL6901820 | 0.88 | PKM (0.32) | GRM5SMN1; SMN2RAB9ANPC1TP53 | |
| SCHEMBL6902406 | 0.87 | TGFBR1 (0.39) | TGFBR1RAB9ANPC1TP53PKM | |
| SCHEMBL6900002 | 0.87 | TRPV1 (0.39) | KDRRAB9ANPC1KDM4EPOLB | |
| SCHEMBL6902284 | 0.85 | KDM4E (0.43) | SMN1; SMN2RAB9ANPC1TP53PKM | |
| SCHEMBL6895444 | 0.85 | CYP1A2 (0.34) | CYP1A2 | |
| SCHEMBL6901048 | 0.83 | KDM4E (0.46) | TGFBR1GRM5SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6902437 | 0.83 | BRS3 (0.38) | SMN1; SMN2RAB9ANPC1CYP1A2MAPT | |
| SCHEMBL6901735 | 0.83 | ALDH1A1 (0.33) | TGFBR1SMN1; SMN2RAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033371-B1 | Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2004-01-28 | — | — | EP | claimed |