Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6895367 | 0.90 | TGFBR1 (0.38) | PKMTP53TGFBR1GRM5KDM4E | |
| SCHEMBL6903067 | 0.88 | NPC1 (0.34) | SYKGRM5KDM4ETDP1CYP1A2 | |
| SCHEMBL6901820 | 0.88 | PKM (0.32) | PKMTP53MEN1KMT2AGRM5 | |
| SCHEMBL6902406 | 0.87 | TGFBR1 (0.39) | PKMTP53MEN1KMT2ATGFBR1 | |
| SCHEMBL6900002 | 0.87 | TRPV1 (0.39) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL6902522 | 0.86 | CCR1 (0.37) | PKMTP53SYKCYP3A4SMN1; SMN2 | |
| SCHEMBL6895444 | 0.85 | CYP1A2 (0.34) | CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6902437 | 0.83 | BRS3 (0.38) | ALDH1A1CYP1A2CYP2D6MAPTCYP2C9 | |
| SCHEMBL6901735 | 0.83 | ALDH1A1 (0.33) | MEN1KMT2ATGFBR1ALDH1A1HPGD | |
| SCHEMBL6902284 | 0.83 | KDM4E (0.43) | PKMTP53MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033371-B1 | Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2004-01-28 | — | — | EP | claimed |