Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 5/20 | 0.32 |
| ▸ | NPC1 | O15118 | 5/20 | 0.32 |
| ▸ | RAB9A | P51151 | 5/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6903610 | 0.88 | PKM (0.40) | PKMSMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL6895367 | 0.88 | TGFBR1 (0.38) | PKMSMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL6903067 | 0.86 | NPC1 (0.34) | SMN1; SMN2NPC1RAB9AMAPTKDM4E | |
| SCHEMBL6902406 | 0.85 | TGFBR1 (0.39) | PKMTP53NPC1RAB9AGAA | |
| SCHEMBL6900002 | 0.85 | TRPV1 (0.39) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL6897160 | 0.84 | CCR1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL6902696 | 0.84 | PDK2 (0.30) | PDK2 | |
| SCHEMBL6895444 | 0.83 | CYP1A2 (0.34) | — | |
| SCHEMBL6901735 | 0.81 | ALDH1A1 (0.33) | SMN1; SMN2NPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL6902437 | 0.81 | BRS3 (0.38) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033371-B1 | Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2004-01-28 | — | — | EP | claimed |