Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.64 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | PPARD | Q03181 | 6/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134587 | 1.00 | ALDH1A1 (0.71) | ALDH1A1ENPEPFFAR4FFAR1AKR1B1 | |
| SCHEMBL3763505 | 0.98 | ALDH1A1 (0.75) | ALDH1A1ENPEPFFAR4FFAR1GPR84 | |
| SCHEMBL1883310 | 0.98 | ALDH1A1 (0.75) | ALDH1A1ENPEPFFAR4FFAR1GPR84 | |
| SCHEMBL1873589 | 0.98 | ALDH1A1 (0.75) | ALDH1A1ENPEPFFAR4FFAR1GPR84 | |
| SCHEMBL1879196 | 0.98 | ALDH1A1 (0.75) | ALDH1A1ENPEPFFAR4FFAR1GPR84 | |
| SCHEMBL1881298 | 0.98 | ALDH1A1 (0.75) | ALDH1A1ENPEPFFAR4FFAR1GPR84 | |
| SCHEMBL1874205 | 0.98 | ALDH1A1 (0.75) | ALDH1A1ENPEPFFAR4FFAR1GPR84 | |
| SCHEMBL1879117 | 0.98 | ALDH1A1 (0.75) | ALDH1A1ENPEPFFAR4FFAR1GPR84 | |
| SCHEMBL1873944 | 0.98 | ALDH1A1 (0.75) | ALDH1A1ENPEPFFAR4FFAR1GPR84 | |
| Hydrochloric Acid SCHEMBL1232665 | 0.98 | ALDH1A1 (0.69) | ALDH1A1ENPEPFFAR4FFAR1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063960-A1 | Process of preparing 3S-3-amino-3-aryl propionic acid and derivatives thereof | SCOTT LORRAINE (US) | 2004-04-01 | — | — | US | disclosed |
| US-20040063960-A1 | Process of preparing 3S-3-amino-3-aryl propionic acid and derivatives thereof | SCOTT LORRAINE (US) | 2004-04-01 | — | — | US | disclosed |
| US-20040063960-A1 | Process of preparing 3S-3-amino-3-aryl propionic acid and derivatives thereof | SCOTT LORRAINE (US) | 2004-04-01 | — | — | US | disclosed |
| US-6673926-B2 | SUCH AS 3-((TERT-BUTOXY)CARBONYL)AMINO-3-(3'-PYRIDYL)PROPIONIC ACID; FOR TREATING PLATELET-MEDIATED THROMBOTIC DISORDERS | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-01-06 | — | — | US | disclosed |
| US-6673926-B2 | SUCH AS 3-((TERT-BUTOXY)CARBONYL)AMINO-3-(3'-PYRIDYL)PROPIONIC ACID; FOR TREATING PLATELET-MEDIATED THROMBOTIC DISORDERS | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-01-06 | — | — | US | disclosed |
| US-20030176471-A1 | Chemical intermediates | SCOTT LORRAINE (US) | 2003-09-18 | — | — | US | disclosed |
| US-20030176471-A1 | Chemical intermediates | SCOTT LORRAINE (US) | 2003-09-18 | — | — | US | disclosed |
| US-20030176471-A1 | Chemical intermediates | SCOTT LORRAINE (US) | 2003-09-18 | — | — | US | disclosed |
| CN-1362948-A | Preparation method of 3S-3-amino-3-aryl propionic acid and derivatives thereof | ORTHO MCNEIL PHARM INC (US) | 2002-08-07 | — | — | CN | disclosed |
| CN-1362948-A | Preparation method of 3S-3-amino-3-aryl propionic acid and derivatives thereof | ORTHO MCNEIL PHARM INC (US) | 2002-08-07 | — | — | CN | disclosed |
| US-20020068829-A1 | Process of preparing 3S-3-amino-3-aryl proprionic acid and derivatives thereof | SCOTT LORRAINE (US) | 2002-06-06 | — | — | US | disclosed |
| US-20020068829-A1 | Process of preparing 3S-3-amino-3-aryl proprionic acid and derivatives thereof | SCOTT LORRAINE (US) | 2002-06-06 | — | — | US | disclosed |
| EP-1163222-A1 | PROCESS OF PREPARING 3S-3-AMINO-3-ARYL PROPIONIC ACID AND DERIVATIVES THEREOF | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2001-12-19 | — | — | EP | disclosed |
| EP-1163222-A1 | PROCESS OF PREPARING 3S-3-AMINO-3-ARYL PROPIONIC ACID AND DERIVATIVES THEREOF | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000056715-A1 | PROCESS OF PREPARING 3S-3-AMINO-3-ARYL PROPIONIC ACID AND DERIVATIVES THEREOF | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2000-09-28 | — | — | WO | disclosed |
| WO-2000056715-A1 | PROCESS OF PREPARING 3S-3-AMINO-3-ARYL PROPIONIC ACID AND DERIVATIVES THEREOF | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2000-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020068829-A1 | Process of preparing 3S-3-amino-3-aryl proprionic acid and derivatives thereof | GABRA6, GABRD, GABBR2 | ALDH1A1 51/4885ENPEP 1210/4885FFAR4 1692/4885 |
| US-20040063960-A1 | Process of preparing 3S-3-amino-3-aryl propionic acid and derivatives thereof | AADAT, ALAD, DDC | ALDH1A1 213/4885ENPEP 122/4885FFAR4 676/4885 |
| US-20030176471-A1 | Chemical intermediates | BCAT1, CYP3A43, AADAT | ALDH1A1 51/4885ENPEP 373/4885FFAR4 1503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.