Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7600113 | 1.00 | TSHR (0.54) | TSHRALDH1A1CES2CYP3A4HPGD | |
| Acetic Acid SCHEMBL28723481 | 0.95 | TSHR (0.59) | TSHRALDH1A1CES2CYP3A4HPGD | |
| Acetic Acid SCHEMBL9616198 | 0.95 | TSHR (0.59) | TSHRALDH1A1CES2CYP3A4HPGD | |
| Acetic Acid SCHEMBL37245 | 0.95 | TSHR (0.59) | TSHRALDH1A1CES2CYP3A4HPGD | |
| Acetic Acid SCHEMBL5480554 | 0.93 | TSHR (0.60) | TSHRALDH1A1CES2CYP3A4HPGD | |
| Acetic Acid SCHEMBL14759095 | 0.92 | TSHR (0.56) | TSHRALDH1A1CES2CYP3A4HPGD | |
| Acetic Acid SCHEMBL16761012 | 0.92 | TSHR (0.56) | TSHRALDH1A1CES2CYP3A4HPGD | |
| Acetic Acid SCHEMBL29287060 | 0.92 | TSHR (0.56) | TSHRALDH1A1CES2CYP3A4HPGD | |
| Acetic Acid SCHEMBL1996435 | 0.92 | TSHR (0.56) | TSHRALDH1A1CES2CYP3A4HPGD | |
| Acetic Acid SCHEMBL4617603 | 0.92 | TSHR (0.56) | TSHRALDH1A1CES2CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133631-A1 | VETERINARY COMPOSITION COMPRISING OCLACITINIB | KRKA, D.D., NOVO MESTO (SI) | 2024-06-27 | — | — | WO | disclosed |
| US-20230414576-A1 | LONG-ACTING SPIRO-ISOXAZOLINE ANTIPARASITIC COMPOSITIONS | ZOETIS SERVICES LLC | 2023-12-28 | — | — | US | disclosed |
| EP-4025209-A1 | PALATABLE SOFT-CHEW | Elanco US Inc. (US) | 2022-07-13 | — | — | EP | disclosed |
| US-20210379023-A1 | LONG-ACTING SPIRO-ISOXAZOLINE ANTIPARASITIC COMPOSITIONS | ZOETIS LLC | 2021-12-09 | — | — | US | disclosed |
| US-20210068425-A1 | PALATABLE GRANULAR VETERINARY COMPOSITIONS | BAYER HEALTHCARE LLC | 2021-03-11 | — | — | US | disclosed |
| US-20210069104-A1 | PALATABLE SOFT-CHEW | BAYER HEALTHCARE LLC | 2021-03-11 | — | — | US | disclosed |
| WO-2021046296-A1 | PALATABLE SOFT-CHEW | BAYER HEALTHCARE LLC (US) | 2021-03-11 | — | — | WO | disclosed |
| US-20210051969-A1 | RECOMBINANTLY EXPRESSED TASTE MODIFYING POLYPEPTIDES AND PREPARATIONS AND FORMULATIONS COMPRISING THE SAME | OOBLI, INC. | 2021-02-25 | — | — | US | disclosed |
| EP-2983712-B1 | COMPOSITION OF MACROCYCLIC LACTONES, LEVAMISOLE, AN AMINO SUGAR AND AN ADDITIONAL ANTIPARASITIC AGENT | ZOETIS SERVICES LLC (US) | 2020-11-25 | — | — | EP | disclosed |
| WO-2019173541-A1 | RECOMBINANTLY EXPRESSED TASTE MODIFYING POLYPEPTIDES AND PREPARATIONS AND FORMULATIONS COMPRISING THE SAME | MIRACULEX, INC. (US) | 2019-09-12 | — | — | WO | disclosed |
| US-20170354593-A1 | PALATABLE CHEWABLE VETERINARY COMPOSITION | ZOETIS SERVICES LLC | 2017-12-14 | — | — | US | disclosed |
| EP-2999339-A1 | LONG-ACTING SPIRO-ISOXAZOLINE ANTIPARASITIC COMPOSITIONS | Zoetis Services LLC (US) | 2016-03-30 | — | — | EP | disclosed |
| US-20160081986-A1 | LONG-ACTING SPIRO-ISOXAZOLINE ANTIPARASITIC COMPOSITIONS | ZOETIS SERVICES LLC (US) | 2016-03-24 | — | — | US | disclosed |
| US-20160051524-A1 | STABLE VETERINARY COMBINATION FORMULATIONS OF MACROCYCLIC LACTONES AND IMIDAZOTHIAZOLES | ZOETIS SERVICES LLC (US) | 2016-02-25 | — | — | US | disclosed |
| EP-2983712-A1 | COMPOSITION OF MACROCYCLIC LACTONES, LEVAMISOLE, AN AMINO SUGAR AND AN ADDITIONAL ANTIPARASITIC AGENT | Zoetis Services LLC (US) | 2016-02-17 | — | — | EP | disclosed |
| WO-2014169092-A1 | COMPOSITION OF MACROCYCLIC LACTONES, LEVAMISOLE, AN AMINO SUGAR AND AN ADDITIONAL ANTIPARASITIC AGENT | ZOETIS LLC (US) | 2014-10-16 | — | — | WO | disclosed |
| US-20040075802-A1 | Sealant for liquid crystal display cell, composition for liquid crystal display cell sealant and liquid crystal display element | MITSUI CHEMICALS, INC. (JP) | 2004-04-22 | — | — | US | disclosed |
| US-6555187-B1 | Mixture of specified physical properties of an epoxy resin, rubber-like polymer fine particles, inorganic filler, curing agent; use in single layer press hot bonding system, high productivity and humidity resistant | MITSUI CHEMICALS, INC. (JP) | 2003-04-29 | — | — | US | disclosed |
| EP-1153952-A1 | SEALING AGENT FOR LIQUID-CRYSTAL DISPLAY CELL, COMPOSITION FOR SEALING AGENT FOR LIQUID-CRYSTAL DISPLAY CELL, AND LIQUID-CRYSTAL DISPLAY ELEMENT | Mitsui Chemicals, Inc. (JP) | 2001-11-14 | — | — | EP | disclosed |
| US-3960610-A | Process for coating metals | AMCHEM PRODUCTS, INC. (US) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230414576-A1 | LONG-ACTING SPIRO-ISOXAZOLINE ANTIPARASITIC COMPOSITIONS | ADRA1B, ADRA1A, ADRA2B | TSHR 743/4885ALDH1A1 48/4885CES2 3031/4885 |
| US-20210069104-A1 | PALATABLE SOFT-CHEW | TAS2R40, TAS2R45, TAS2R42 | TSHR 3543/4885ALDH1A1 2225/4885CES2 1094/4885 |
| US-20170354593-A1 | PALATABLE CHEWABLE VETERINARY COMPOSITION | PIGS, TAS2R31, TAS2R42 | TSHR 3831/4885ALDH1A1 3413/4885CES2 3842/4885 |
| US-20210379023-A1 | LONG-ACTING SPIRO-ISOXAZOLINE ANTIPARASITIC COMPOSITIONS | ADRA1B, ADRA1A, ADRA2B | TSHR 743/4885ALDH1A1 48/4885CES2 3031/4885 |
| US-20210068425-A1 | PALATABLE GRANULAR VETERINARY COMPOSITIONS | PIGS, VMA21, PGA5 | TSHR 4348/4885ALDH1A1 3293/4885CES2 4788/4885 |
| US-20160081986-A1 | LONG-ACTING SPIRO-ISOXAZOLINE ANTIPARASITIC COMPOSITIONS | ADRA1B, ADRA1A, ADRA2B | TSHR 743/4885ALDH1A1 48/4885CES2 3031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.