SCHEMBL692064

SCHEMBL692064

O=Cc1cc2ccccc2cc1N(C=O)OCc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
ALOX5 P09917 1/20 0.37
RAB9A P51151 2/20 0.37
MAPT P10636 2/20 0.37
NPC1 O15118 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
SRC P12931 1/20 0.35
ALDH1A1 P00352 2/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
POLB P06746 1/20 0.34
HPGD P15428 1/20 0.34
KMT2A Q03164 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
GAA P10253 1/20 0.34
ERN1 O75460 3/20 0.34
PTP4A3 O75365 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL692062 0.81 ALOX5 (0.36) MAOAMAOBALOX5RAB9AMAPT
SCHEMBL7268160 0.81 SLC16A3 (0.41) L3MBTL1ALDH1A1MEN1POLBHPGD
SCHEMBL6936315 0.73 TSHR (0.41) MAOAMAOBMAPTL3MBTL1ALDH1A1
SCHEMBL7404744 0.72 MAOA (0.47) MAOAMAOBALOX5RAB9AMAPT
SCHEMBL692158 0.71 L3MBTL1 (0.55) MAOAMAOBALOX5RAB9AMAPT
SCHEMBL9005245 0.70 MAOA (0.43) MAOAMAOBRAB9AMAPTNPC1
SCHEMBL9626552 0.69 ACHE (0.44) MAOAMAOBRAB9AMAPTSMN1; SMN2
SCHEMBL7304372 0.68 CYP1A2 (0.44) MAPTALDH1A1MEN1LMNAHPGD
SCHEMBL7404742 0.68 NOX1 (0.36) MAOAMAOBALOX5RAB9AMAPT
SCHEMBL9524235 0.68 CYP19A1 (0.48) MAOAMAOBRAB9AMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 617 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043639-B2 Polycationic methyl phospholipids for improved delivery of nucleic acids to eukaryotic cells MOLECULAR TRANSFER, INC. (US) 2024-07-23 US disclosed
EP-4384508-A2 LIPIDS FOR NUCLEIC ACID DELIVERY Life Technologies Corporation (US) 2024-06-19 EP disclosed
WO-2024031051-A1 LIPIDS FOR NUCLEIC ACID DELIVERY Life Technologies Corporation (US) 2024-02-08 WO disclosed
US-20240000966-A1 Lipid Compositions For In Vivo Delivery Life Technologies Corporation 2024-01-04 US disclosed
WO-2024006937-A1 LIPID COMPOSITIONS FOR IN VIVO DELIVERY Life Technologies Corporation (US) 2024-01-04 WO disclosed
US-11850237-B2 Compounds and methods for treating influenza ROMARK LABORATORIES L.C. (US) 2023-12-26 US disclosed
WO-2023018990-A2 LIPIDS FOR NUCLEIC ACID DELIVERY Life Technologies Corporation (US) 2023-02-16 WO disclosed
EP-2445349-B1 COMPOUNDS AND METHODS FOR TREATING INFLUENZA ROMARK LABORATORIES LC (US) 2022-02-09 EP disclosed
US-20210323984-A1 POL YCATIONIC METHYL PHOSPHOLIPIDS FOR IMPROVED DELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS MOLECULAR TRANSFER, INC. 2021-10-21 US disclosed
EP-3895706-A1 THIAZOLINIDE COMPOUNDS FOR TREATING NON-INFLUENZA VIRAL INFECTIONS Romark Laboratories, L.C. (US) 2021-10-20 EP disclosed
EP-0558603-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1993-09-08 EP disclosed
EP-0554400-A1 RETROVIRAL PROTEASE INHIBITORS. MONSANTO CO (US) 1993-08-11 EP disclosed
US-5157041-A Viricides HOFFMANN-LA ROCHE INC. (US) 1992-10-20 US disclosed
WO-1992008701-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed
WO-1992008700-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed
WO-1992008698-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed
WO-1992008699-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed
WO-1992008688-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed
EP-0432694-A2 Aminoalcohols F. HOFFMANN-LA ROCHE AG (CH) 1991-06-19 EP disclosed
EP-0346847-A2 Amino acid derivatives F. HOFFMANN-LA ROCHE AG (CH) 1989-12-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12043639-B2 Polycationic methyl phospholipids for improved delivery of nucleic acids to eukaryotic cells PHOSPHO1, MBOAT7, PLTP MAOA 4847/4885MAOB 4799/4885ALOX5 2942/4885
US-20240000966-A1 Lipid Compositions For In Vivo Delivery CHMP4B, LIPA, CETP MAOA 4854/4885MAOB 4825/4885ALOX5 1717/4885
US-11850237-B2 Compounds and methods for treating influenza HIF1AN, HAVCR2, NEU1 MAOA 28/4885MAOB 38/4885ALOX5 1315/4885
US-20210323984-A1 POL YCATIONIC METHYL PHOSPHOLIPIDS FOR IMPROVED DELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS POLRMT, PHOSPHO1, MBOAT7 MAOA 4526/4885MAOB 4648/4885ALOX5 3016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.