Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PARG | Q86W56 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | IDH2 | P48735 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940841 | 0.81 | KMT2A (0.35) | ALDH1A1L3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6941830 | 0.81 | KDM4E (0.30) | ALDH1A1L3MBTL1SMN1; SMN2POLBKMT2A | |
| SCHEMBL6934900 | 0.81 | LMNA (0.33) | ALDH1A1POLBLMNATHRB | |
| SCHEMBL6935282 | 0.78 | GSTO1 (0.38) | ALDH1A1LMNA | |
| SCHEMBL6937780 | 0.78 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2POLBKMT2AMEN1 | |
| SCHEMBL6939756 | 0.78 | GRIN2D (0.33) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL6938296 | 0.76 | CA1 (0.42) | L3MBTL1SMN1; SMN2POLBLMNATHRB | |
| SCHEMBL6937183 | 0.76 | PGR (0.48) | BRD4L3MBTL1POLBKMT2AMEN1 | |
| SCHEMBL6934342 | 0.76 | L3MBTL1 (0.40) | BRD4ALDH1A1L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL6938457 | 0.75 | BCAT1 (0.35) | THRBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1125942-B1 | Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-09 | — | — | EP | disclosed |
| EP-1125942-A1 | Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-08-22 | — | — | EP | disclosed |