SCHEMBL6937368

SCHEMBL6937368

Cc1ccc(S(=O)(=O)Oc2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.54
CA1 P00915 1/20 0.54
CA9 Q16790 1/20 0.54
ENPP3 O14638 7/20 0.53
ENPP1 P22413 6/20 0.53
ENPP2 Q13822 5/20 0.53
ALDH1A1 P00352 3/20 0.50
KIF11 P52732 1/20 0.50
BCHE P06276 1/20 0.50
ACHE P22303 1/20 0.50
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
CA12 O43570 2/20 0.47
MAPT P10636 2/20 0.47
HTT P42858 1/20 0.47
PPARG P37231 1/20 0.47
PTPN1 P18031 1/20 0.47
RECQL P46063 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6549310 1.00 CA2 (0.54) CA2CA1CA9ENPP3ENPP1
SCHEMBL3843869 0.87 ENPP1 (0.47) CA2CA1CA9ENPP3ENPP1
SCHEMBL18179825 0.86 MEN1 (0.60) CA2CA1CA9ENPP3ENPP1
SCHEMBL4126086 0.86 MEN1 (0.60) CA2CA1CA9ENPP3ENPP1
SCHEMBL9852204 0.86 MEN1 (0.60) CA2CA1CA9ENPP3ENPP1
SCHEMBL3841628 0.85 KMT2A (0.51) CA2CA1CA9ENPP3ENPP1
SCHEMBL2065585 0.85 CA1 (0.56) CA2CA1CA9ENPP3ENPP1
SCHEMBL2990067 0.85 MEN1 (0.62) CA2CA1CA9ENPP3ENPP1
SCHEMBL12276116 0.84 BCHE (0.58) CA2CA1CA9ALDH1A1KIF11
Iodide SCHEMBL22068772 0.84 CA2 (0.59) CA2CA1CA9ENPP3ENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10463391-B2 Magnetic ferrocenyl-functionalized nanoparticle KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2019-11-05 US disclosed
US-10370397-B2 Phosphine substituted ferrocenyl complex Kind Fahd University of Petroleum and Minerals (SA) 2019-08-06 US disclosed
EP-2949655-B1 REACTION CATALYST FOR CROSS COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND HOKKO CHEM IND CO (JP) 2019-05-15 EP disclosed
US-20190029718-A1 MAGNETIC FERROCENYL-FUNCTIONALIZED NANOPARTICLE KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2019-01-31 US disclosed
US-20190031697-A1 PHOSPHINE SUBSTITUTED FERROCENYL COMPLEX KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2019-01-31 US disclosed
US-10150110-B2 Method for making and using a solid-supported catalyst KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2018-12-11 US disclosed
US-10150109-B2 Palladium(II)-silica supported catalyst KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2018-12-11 US disclosed
US-10150111-B2 Method for catalytic synthesis of cinnamic acid with catalyst recycle KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2018-12-11 US disclosed
US-20180326409-A1 METHOD FOR MAKING AND USING A SOLID-SUPPORTED CATALYST KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2018-11-15 US disclosed
US-20180326410-A1 METHOD FOR CATALYTIC SYNTHESIS OF CINNAMIC ACID WITH CATALYST RECYCLE KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2018-11-15 US disclosed
US-20150360214-A1 REACTION CATALYST FOR CROSS-COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 2015-12-17 US disclosed
EP-2949655-A1 REACTION CATALYST FOR CROSS COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND Hokko Chemical Industry Co., Ltd. (JP) 2015-12-02 EP disclosed
EP-2701230-A1 NONAQUEOUS ELECTROLYTE SOLUTION, ELECTRICITY STORAGE DEVICE USING SAME, AND TRIFLUOROMETHYLBENZENE COMPOUND Ube Industries, Ltd. (JP) 2014-02-26 EP disclosed
US-20140038060-A1 NONAQUEOUS ELECTROLYTE SOLUTION, ELECTRICITY STORAGE DEVICE USING SAME, AND TRIFLUOROMETHYLBENZENE COMPOUND UBE INDUSTRIES, LTD. (JP) 2014-02-06 US disclosed
EP-1167372-B1 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst TAKASAGO PERFUMERY CO LTD (JP) 2003-12-10 EP disclosed
US-6455720-B1 AS CATALYSTS TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-09-24 US disclosed
US-20020058837-A1 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-05-16 US disclosed
US-6365776-B1 FROM ORGANOHALOGEN COMPOUND AND AMINE USING PALLADIUM COMPOUND CATALYST AND PROMOTER TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-04-02 US disclosed
US-20020035295-A1 PROCESS FOR PRODUCING AROMATIC AMINES TAKASAGO INTERNATIONAL CORPORATION 2002-03-21 US disclosed
EP-1167372-A1 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst Takasago International Corporation (JP) 2002-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10150109-B2 Palladium(II)-silica supported catalyst PDK2, SIK2, SIK1 CA2 1223/4885CA1 1516/4885CA9 560/4885
US-20180326409-A1 METHOD FOR MAKING AND USING A SOLID-SUPPORTED CATALYST AOC1, SOD1, PDK2 CA2 1949/4885CA1 1369/4885CA9 430/4885
US-20020035295-A1 PROCESS FOR PRODUCING AROMATIC AMINES TYR, DDC, PNMT CA2 3856/4885CA1 4452/4885CA9 2329/4885
US-20020058837-A1 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst DDT, PDCD11, PLD2 CA2 3780/4885CA1 4340/4885CA9 3088/4885
US-20180326410-A1 METHOD FOR CATALYTIC SYNTHESIS OF CINNAMIC ACID WITH CATALYST RECYCLE DDT, PDK2, CLK2 CA2 1027/4885CA1 1145/4885CA9 304/4885
US-10370397-B2 Phosphine substituted ferrocenyl complex FECH, PHOSPHO1, FTH1 CA2 1884/4885CA1 1368/4885CA9 614/4885
US-20190031697-A1 PHOSPHINE SUBSTITUTED FERROCENYL COMPLEX FECH, FOLR1, FOLR2 CA2 1584/4885CA1 751/4885CA9 784/4885
US-10150111-B2 Method for catalytic synthesis of cinnamic acid with catalyst recycle DDT, PDK2, CLK2 CA2 1027/4885CA1 1145/4885CA9 304/4885
US-20150360214-A1 REACTION CATALYST FOR CROSS-COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND ALK, HRH4, HRH3 CA2 163/4885CA1 952/4885CA9 411/4885
US-10150110-B2 Method for making and using a solid-supported catalyst AOC1, SOD1, PDK2 CA2 1949/4885CA1 1369/4885CA9 430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.