Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.55 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.44 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1908735 | 1.00 | MAPK1 (0.57) | MAPK1CYP3A4TAAR1SLC18A2SIGMAR1 | |
| SCHEMBL1396350 | 1.00 | MAPK1 (0.57) | MAPK1CYP3A4TAAR1SLC18A2SIGMAR1 | |
| Carbamic Acid SCHEMBL28108902 | 0.91 | MAPK1 (0.58) | MAPK1CYP3A4TAAR1SLC18A2SIGMAR1 | |
| SCHEMBL1697045 | 0.87 | SIGMAR1 (0.64) | TAAR1SLC18A2SIGMAR1EPHX1OPRM1 | |
| SCHEMBL2293359 | 0.85 | ACACB (0.47) | MAPK1CYP3A4TAAR1SLC18A2SIGMAR1 | |
| SCHEMBL2293880 | 0.85 | ACACB (0.47) | MAPK1CYP3A4TAAR1SLC18A2SIGMAR1 | |
| SCHEMBL7345520 | 0.85 | MAPK1 (0.58) | MAPK1CYP3A4SIGMAR1TRPA1KDM4E | |
| SCHEMBL7348151 | 0.85 | MAPK1 (0.58) | MAPK1CYP3A4SIGMAR1TRPA1KDM4E | |
| SCHEMBL12992873 | 0.84 | MAPK1 (0.44) | MAPK1CYP3A4TAAR1SLC18A2SIGMAR1 | |
| SCHEMBL12379288 | 0.84 | LTA4H (0.53) | MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260109721-A1 | IONIZABLE CATIONIC LIPIDS INCORPORATING SILICON: SYNTHESIS AND LNP FORMULATION | ALDEXCHEM KFT (HU) | 2026-04-23 | — | — | US | disclosed |
| EP-4646422-A1 | IONIZABLE CATIONIC LIPIDS INCORPORATING SILICON: SYNTHESIS AND LNP FORMULATION | AldexChem Kft. (HU) | 2025-11-12 | — | — | EP | disclosed |
| WO-2025052296-A1 | IONIZABLE CATIONIC LIPIDS INCORPORATING SILICON: SYNTHESIS AND LNP FORMULATION | ALDEXCHEM KFT. (HU) | 2025-03-13 | — | — | WO | disclosed |
| EP-4310093-A1 | AMINO ACID DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION FOR TREATING HEPATITIS, COMPRISING SAME | Prazertherapeutics Inc. (KR) | 2024-01-24 | — | — | EP | disclosed |
| US-20230312646-A1 | ANTIBACTERIAL PEPTIDES | Universite de Bordeaux (FR) | 2023-10-05 | — | — | US | disclosed |
| WO-2023020789-A1 | METHODS FOR PREPARING OXAZABOROLIDINES | PATHWAY INTERMEDIATES LIMITED (GB) | 2023-02-23 | — | — | WO | disclosed |
| US-10266506-B2 | Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system or of tumors | PIRAMAL IMAGING SA (CH) | 2019-04-23 | — | — | US | disclosed |
| US-10266506-B2 | Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system or of tumors | PIRAMAL IMAGING SA (CH) | 2019-04-23 | — | — | US | disclosed |
| EP-2630104-B1 | COMPOUNDS FOR USE IN IMAGING, DIAGNOSING AND/OR TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM | PIRAMAL IMAGING SA (CH) | 2018-04-04 | — | — | EP | disclosed |
| EP-2630104-B1 | COMPOUNDS FOR USE IN IMAGING, DIAGNOSING AND/OR TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM | PIRAMAL IMAGING SA (CH) | 2018-04-04 | — | — | EP | disclosed |
| US-20030040483-A1 | Compounds with growth hormone releasing properties | HELSINN THERAPEUTICS (U.S.), INC. | 2003-02-27 | — | — | US | disclosed |
| US-6350767-B1 | GROWTH HORMONE RELEASE STIMULANT | NOVO NORDISK A/S (DK) | 2002-02-26 | — | — | US | disclosed |
| US-6127391-A | A PEPTIDE MIMETIC COMPOUND FOR STIMULATING THE RELEASE OF GROWTH HORMONE FROM THE PITUITARY | NOVO NORDISK A/S (DK) | 2000-10-03 | — | — | US | disclosed |
| US-6013658-A | ANIMAL GROWTH REGULATORS | NOVO NORDISK A/S (DK) | 2000-01-11 | — | — | US | disclosed |
| US-5977178-A | Compounds with growth hormone releasing properties | NOVO NORDISK A/S (DK) | 1999-11-02 | — | — | US | disclosed |
| EP-0869974-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1998-10-14 | — | — | EP | disclosed |
| EP-0805816-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-11-12 | — | — | EP | disclosed |
| WO-1997023508-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-07-03 | — | — | WO | disclosed |
| WO-1996022997-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-01 | — | — | WO | disclosed |
| WO-1994007841-A1 | PROCESS FOR REDUCING CARBOXYLIC ACIDS OR CARBOXYLIC ACID DERIVATIVES, AND NOVEL COMPOUNDS | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1994-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10266506-B2 | Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system or of tumors | PMP22, MEN1, VHL | MAPK1 2939/4885CYP3A4 4602/4885TAAR1 642/4885 |
| US-20030040483-A1 | Compounds with growth hormone releasing properties | GHRHR, GHSR, GRPR | MAPK1 1036/4885CYP3A4 3566/4885TAAR1 481/4885 |
| US-20260109721-A1 | IONIZABLE CATIONIC LIPIDS INCORPORATING SILICON: SYNTHESIS AND LNP FORMULATION | SGMS1, SGMS2, AGO2 | MAPK1 2335/4885CYP3A4 4841/4885TAAR1 3695/4885 |
| US-20230312646-A1 | ANTIBACTERIAL PEPTIDES | VIP, NRDC, CLPP | MAPK1 2451/4885CYP3A4 4695/4885TAAR1 4854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.