Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937466 | 0.92 | DPP4 (0.35) | TRPA1MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL6937028 | 0.90 | TRPA1 (0.38) | TRPA1MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL6937419 | 0.90 | P2RX7 (0.39) | TRPA1KMT2ASLC6A2SLC6A4OPRM1 | |
| SCHEMBL6937424 | 0.86 | TRPA1 (0.44) | TRPA1MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL6937427 | 0.85 | TRPA1 (0.38) | TRPA1MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL6939503 | 0.85 | TRPA1 (0.36) | TRPA1MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL5845144 | 0.83 | TRPA1 (0.35) | TRPA1MEN1KMT2ASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL5846909 | 0.82 | TRPA1 (0.34) | TRPA1MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL6941995 | 0.81 | ESR1 (0.37) | TRPA1MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL5846181 | 0.81 | ALDH1A1 (0.38) | TRPA1MEN1KMT2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043307-B1 | 3-amino-3-arylpropan-1-ol-derivates, their preparation and their use | GRUENENTHAL GMBH (DE) | 2003-06-04 | — | — | EP | claimed |
| US-6410790-B1 | ANALGESICS | GRUENENTHAL GMBH (DE) | 2002-06-25 | — | — | US | claimed |
| US-6410790-B1 | ANALGESICS | GRUENENTHAL GMBH (DE) | 2002-06-25 | — | — | US | disclosed |