Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT5 | Q96KN8 | 3/20 | 0.48 |
| ▸ | PLAAT4 | Q9UL19 | 3/20 | 0.48 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.48 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942862 | 0.85 | CA12 (0.46) | PLAAT5PLAAT4PLAAT3PLAAT2ALDH1A1 | |
| SCHEMBL9006857 | 0.84 | TDP1 (0.56) | ALDH1A1KEAP1NPC1RAB9AHDAC2 | |
| SCHEMBL991969 | 0.83 | ALDH1A1 (0.57) | PLAAT5PLAAT4PLAAT3PLAAT2ALDH1A1 | |
| SCHEMBL27514725 | 0.76 | KEAP1 (0.55) | PLAAT5PLAAT4PLAAT3PLAAT2ALDH1A1 | |
| SCHEMBL313265 | 0.74 | FFAR1 (0.61) | PLAAT5PLAAT4PLAAT3PLAAT2HDAC2 | |
| SCHEMBL304796 | 0.73 | L3MBTL1 (0.55) | PLAAT5PLAAT4PLAAT3PLAAT2ALDH1A1 | |
| SCHEMBL27883810 | 0.73 | ALDH1A1 (0.58) | PLAAT5PLAAT4PLAAT3PLAAT2ALDH1A1 | |
| SCHEMBL7640251 | 0.73 | PLAAT3 (0.58) | PLAAT5PLAAT4PLAAT3PLAAT2ALDH1A1 | |
| SCHEMBL750022 | 0.73 | TSHR (0.51) | ALDH1A1RAB9AHDAC8HDAC6TDP1 | |
| SCHEMBL4279627 | 0.73 | KEAP1 (0.73) | PLAAT5PLAAT4ALDH1A1KEAP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827943-B1 | PROCESSES FOR THE REDUCTION OF CARBONYL COMPOUNDS | KANEKA CORP (JP) | 2003-05-21 | — | — | EP | disclosed |
| US-6150567-A | REACTING CARBONYL COMPOUND WITH ORGANOALUMINUM COMPOUND TO FORM AN ALCOHOL COMPOUND | KANEKA CORPORATION (JP) | 2000-11-21 | — | — | US | disclosed |
| EP-0827943-A1 | PROCESSES FOR THE REDUCTION OF CARBONYL COMPOUNDS | KANEKA CORPORATION (JP) | 1998-03-11 | — | — | EP | disclosed |