Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944566 | 0.81 | P2RX3 (0.31) | — | |
| SCHEMBL7937125 | 0.81 | ALDH1A1 (0.31) | SLC6A3GAA | |
| SCHEMBL7930228 | 0.79 | CTSC (0.33) | SLC6A3 | |
| SCHEMBL6939590 | 0.75 | P2RX3 (0.36) | MEN1KMT2AHPGD | |
| SCHEMBL6947400 | 0.71 | ADAM17 (0.46) | SLC6A3GAA | |
| SCHEMBL6937845 | 0.71 | ADAM17 (0.46) | SLC6A3GAA | |
| SCHEMBL6941960 | 0.71 | ADAM17 (0.33) | MEN1KMT2AGAA | |
| SCHEMBL7928806 | 0.71 | P2RX3 (0.34) | SLC6A3GAA | |
| SCHEMBL8112771 | 0.71 | SLC6A3 (0.31) | SLC6A3 | |
| SCHEMBL7940281 | 0.70 | CCNA2 (0.31) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993442-B1 | HYDRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |
| EP-0993442-A1 | HYDRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-04-19 | — | — | EP | disclosed |
| WO-1999001428-A1 | HYDRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-01-14 | — | — | WO | disclosed |