Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944569 | 0.81 | SLC6A3 (0.32) | — | |
| SCHEMBL7937124 | 0.80 | P2RX3 (0.32) | P2RX3 | |
| SCHEMBL7930219 | 0.77 | TGFBR1 (0.31) | P2RX3 | |
| SCHEMBL7928806 | 0.74 | P2RX3 (0.34) | P2RX3 | |
| SCHEMBL8112771 | 0.72 | SLC6A3 (0.31) | P2RX3 | |
| SCHEMBL6941959 | 0.70 | P2RX3 (0.34) | P2RX3 | |
| SCHEMBL6939588 | 0.70 | P2RX3 (0.37) | P2RX3 | |
| SCHEMBL8097948 | 0.69 | P2RX3 (0.31) | P2RX3 | |
| SCHEMBL7930228 | 0.68 | CTSC (0.33) | P2RX3 | |
| SCHEMBL6941960 | 0.68 | ADAM17 (0.33) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993442-B1 | HYDRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |
| EP-0993442-A1 | HYDRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-04-19 | — | — | EP | disclosed |
| WO-1999001428-A1 | HYDRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-01-14 | — | — | WO | disclosed |