Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 7/20 | 0.71 |
| ▸ | MKNK2 | Q9HBH9 | 7/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.54 |
| ▸ | KIF11 | P52732 | 1/20 | 0.53 |
| ▸ | KMO | O15229 | 1/20 | 0.53 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.52 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27605181 | 0.85 | MKNK1 (0.76) | MKNK1MKNK2MAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL13712389 | 0.84 | CYP11B2 (0.72) | MKNK1MKNK2CYP3A4CYP1A2CYP19A1 | |
| SCHEMBL18943256 | 0.84 | KMO (0.60) | MKNK1MKNK2MAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL29788154 | 0.83 | MKNK1 (1.00) | MKNK1MKNK2CYP3A4CYP2A6ALDH1A1 | |
| SCHEMBL208351 | 0.83 | MKNK1 (1.00) | MKNK1MKNK2CYP3A4CYP2A6ALDH1A1 | |
| SCHEMBL2277474 | 0.82 | NPC1 (0.66) | SMN1; SMN2CYP3A4ALDH1A1CYP1A2NPC1 | |
| SCHEMBL4426460 | 0.82 | KMO (0.73) | MKNK1MKNK2CYP3A4CYP2A6ALDH1A1 | |
| SCHEMBL14621505 | 0.82 | MKNK1 (0.59) | MKNK1MKNK2CYP3A4CYP2A6ALDH1A1 | |
| SCHEMBL606654 | 0.81 | MKNK1 (1.00) | MKNK1MKNK2CYP3A4CYP2A6ALDH1A1 | |
| SCHEMBL30855339 | 0.81 | MKNK1 (1.00) | MKNK1MKNK2CYP3A4CYP2A6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573086-A1 | METHANOGEN INHIBITORS | Agrizeronz Limited Partnership (NZ) | 2025-06-25 | — | — | EP | disclosed |
| CN-119998272-A | Methanogen inhibitors | 阿格里泽伦茨有限合伙公司 | 2025-05-13 | — | — | CN | disclosed |
| WO-2024039250-A1 | METHANOGEN INHIBITORS | PASTORAL GREENHOUSE GAS RESEARCH LIMITED (NZ) | 2024-02-22 | — | — | WO | disclosed |
| WO-2023091644-A2 | HSD17B13-RELATED DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-05-25 | — | — | WO | disclosed |
| US-10784446-B2 | Compound, organic electroluminescence element material, organic electroluminescence element and electronic device | IDEMITSU KOSAN CO., LTD. (JP) | 2020-09-22 | — | — | US | disclosed |
| CN-110563638-A | compound and organic electronic device thereof | 上海嵘彩光电材料有限公司 | 2019-12-13 | — | — | CN | disclosed |
| CN-109988159-A | The diphenylpyrimidin compound and its organic electroluminescent device replaced through pyridine | 昱镭光电科技股份有限公司 | 2019-07-09 | — | — | CN | disclosed |
| US-20170213983-A1 | COMPOUND, ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL, ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2017-07-27 | — | — | US | disclosed |
| US-20170213983-A1 | COMPOUND, ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL, ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2017-07-27 | — | — | US | disclosed |
| US-20130295261-A1 | ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2013-11-07 | — | — | US | disclosed |
| US-8420145-B2 | Isosorbide derivatives and their use as flavor modifiers, tastants, and taste enhancers | SENOMYX, INC. (US) | 2013-04-16 | — | — | US | disclosed |
| EP-1802641-B1 | BISPHOSPHONATE COMPOUNDS AND METHODS FOR BONE RESORPTION DISEASES, CANCER, BONE PAIN, IMMUNE DISORDERS, AND INFECTIOUS DISEASES | UNIV ILLINOIS (US) | 2011-08-10 | — | — | EP | disclosed |
| WO-2010137350-A1 | AGENT FOR TREATMENT OR PREVENTION OF DISEASES ASSOCIATED WITH ACTIVITY OF NEUROTROPHIC FACTORS | 住友化学株式会社 (JP) | 2010-12-02 | — | — | WO | disclosed |
| US-20090220662-A1 | ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS | SENOMYX, INC. | 2009-09-03 | — | — | US | disclosed |
| EP-1075475-B1 | HETEROCYCLIC CARBOXAMIDE DERIVATIVES AS INHIBITORS OF NITRIC OXIDE PRODUCTION | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-06-18 | — | — | EP | disclosed |
| US-20020132809-A1 | Heterocyclic carboxamide derivatives as inhibitors of nitric oxide production | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2002-09-19 | — | — | US | disclosed |
| EP-1075475-A1 | HETEROCYCLIC CARBOXAMIDE DERIVATIVES AS INHIBITORS OF NITRIC OXIDE PRODUCTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-02-14 | — | — | EP | disclosed |
| CN-1056840-C | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 2000-09-27 | — | — | CN | disclosed |
| WO-1999057114-A1 | HETEROCYCLIC CARBOXAMIDE DERIVATIVES AS INHIBITORS OF NITRIC OXIDE PRODUCTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020132809-A1 | Heterocyclic carboxamide derivatives as inhibitors of nitric oxide production | NOS1, NOS3, NOS2 | MKNK1 1529/4885MKNK2 1898/4885MAPT 333/4885 |
| US-20090220662-A1 | ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS | TAS2R10, TAS2R41, TAS2R30 | MKNK1 1636/4885MKNK2 1597/4885MAPT 812/4885 |
| US-10784446-B2 | Compound, organic electroluminescence element material, organic electroluminescence element and electronic device | L1CAM, SOD1, OR10J3 | MKNK1 4120/4885MKNK2 4072/4885MAPT 3405/4885 |
| US-20170213983-A1 | COMPOUND, ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL, ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE | L1CAM, SOD1, OR10J3 | MKNK1 4120/4885MKNK2 4072/4885MAPT 3405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.