SCHEMBL6959688

SCHEMBL6959688

CCC(=O)N1C(=O)CCC1(C(C)C)C(C)C

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6964256 0.77 TP53 (0.40) POLBALDH1A1LMNA
SCHEMBL6966024 0.75 POLB (0.33) POLBALDH1A1LMNA
SCHEMBL27405712 0.67 ALDH1A1 (0.39) ALDH1A1
SCHEMBL2377717 0.62 POLB (0.50) POLBALDH1A1LMNA
SCHEMBL6955467 0.62 NAAA (0.37) ALDH1A1LMNA
SCHEMBL6958441 0.61 TP53 (0.36) ALDH1A1LMNA
SCHEMBL15247314 0.61 OPRM1 (0.41) POLBALDH1A1LMNA
SCHEMBL8779653 0.60 L3MBTL1 (0.38) POLBALDH1A1LMNA
SCHEMBL12259441 0.59 OPRM1 (0.42) POLBALDH1A1LMNA
SCHEMBL6959243 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6340751-B1 REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-01-22 US claimed
EP-0974582-B1 Process for the preparation of 4-substituted azetidinone derivatives TAKASAGO PERFUMERY CO LTD (JP) 2003-02-12 EP disclosed
US-6340751-B1 REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-01-22 US disclosed
EP-0974582-A1 Process for the preparation of 4-substituted azetidinone derivatives Takasago International Corporation (JP) 2000-01-26 EP disclosed