Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | VDR | P11473 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.31 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969927 | 0.91 | IDO1 (0.38) | TDP1KCNH2VDRHTTMEN1 | |
| SCHEMBL6968924 | 0.89 | GABRA5 (0.37) | TDP1MEN1KMT2A | |
| SCHEMBL6972005 | 0.88 | VDR (0.32) | KCNH2VDRMEN1KMT2A | |
| SCHEMBL6964826 | 0.87 | VDR (0.36) | TDP1VDRMEN1KMT2A | |
| SCHEMBL6968696 | 0.86 | ACHE (0.35) | TDP1KCNH2MEN1KMT2AIDO1 | |
| SCHEMBL6968691 | 0.86 | ACHE (0.35) | TDP1KCNH2MEN1KMT2AIDO1 | |
| SCHEMBL4737052 | 0.84 | KCNH2 (0.39) | TDP1KCNH2HTTMEN1KMT2A | |
| SCHEMBL6969836 | 0.84 | HSP90B1 (0.32) | HSP90B1TRAP1 | |
| SCHEMBL6969917 | 0.83 | GRIN1 (0.38) | TDP1VDRHTTKMT2AIDO1 | |
| SCHEMBL6973236 | 0.83 | ALDH1A1 (0.35) | TDP1VDRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |